Project description:The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) is a community-based study where all men and women at age 70 living in Uppsala, Sweden were invited to participate in 2001. The 1,016 participants (50% women) have been extensively phenotyped. In March 2006 a reinvesigation of the cohort at the age of 75 was started. The major measurements performed at age 70 were also repeated at age 75. Here we make publically available all the metabolomics analysis on serum samples from the investigation at age 70. In the final analysis we included samples from 968 individuals.
Project description:Rats were given pulmonary embolism by i.v. injection of 25 micron polystyrene microspheres or 0.01% Tween20 solution as vehicle control Embolism of microspheres is irreversible and causes dose dependent pulmonary hypertension Keywords: time course and dose response
Project description:Blood transcriptional profiling in a prospective observational cohort of South African adults referred for investigation of possible pulmonary tuberculosis