Project description:This dataset contains TMT-10plex quantitative proteomics of serum isolated from monogamous deer mice (Peromyscus). The study investigates the systemic physiological impact of social interactions, specifically comparing pair-bonded animals to those that have experienced bond disruption. The circulating serum proteome was analyzed to identify factors that mediate peripheral tissue responses to social history. This serum data supports findings regarding the impact of social bonds on the lung transcriptome (Naderi et al., 2023, BMC Genomics) and systemic transcriptomic stochasticity/gene canalization in cultured cells.
Project description:Whole transcriptome RNA sequencing in brain tissue was generated to explore differences between young and old animals of two closely related species of deer mice (genus Peromyscus) that reportedly differ in their lifespans: P. leucopus that lives for up to 8 years and P. maniculatus that exhibits a lifespan of about 4 years.