Project description:The CDR1 gene of Trichophyton beardii was knocked out and replenished by ATMT technology. The effect of CDR1 gene on the gene expression profile of Trichophyton beardii was studied by high-throughput sequencing

2025-05-06 | GSE202357 | GEO

Trichophyton mentagrophytes strain:PG12DES

Project description:Trichophyton mentagrophytes strain:PG12DES Genome sequencing

| PRJNA1196900 | ENA

Trichophyton mentagrophytes strain:PG11NEG

Project description:Trichophyton mentagrophytes strain:PG11NEG Genome sequencing

| PRJNA1225126 | ENA

Dermatophytes CGH based on a Trichophyton rubrum cDNA microarray

Project description:A cDNA microarray was constructed from the expressed sequence tags (ESTs) of different developmental stages, and comparative genome hybridization based on microarray procedures were carried out. Dermatophyte species are classified into three genera: Epidermophyton, Microsporum, and Trichophyton. To determine the relationship between these three groups comparative genome hybridization were used in our experiment. Trichophyton rubrum genmic DNA was reference DNA and labelled by Cy3 while the other dermatophytes genomic DNA were test DNA and labelled by CY5. Test and reference DNA were co-hybridized with the T. rubrum cDNA microarray and the numbers of genes shared between each species and T. rubrum were determined. Keywords: Comparative Genomic Hybridization We used a Trichophyton rubrum cDNA microarray prepared in our lab through comparative genome hybridization of genomic DNA of 21 dermatophyte strains (belonging to 20 species) to elucidate the taxonomy and evolution profiles of 20 dermatophyte species. The numbers of genes shared between each species and T. rubrum were determined. Each strain DNA hybridized for 3 times. The slides were separated into three groups base on different datasets.

2010-05-03 | E-GEOD-7909 | biostudies-arrayexpress

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