Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Ealy-life URT microbiome in calves

PROVIDER: PRJNA1259590 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR33452002_1.fastq.gz	Fastqsanger.gz
	SRR33452002_2.fastq.gz	Fastqsanger.gz
	SRR33452005_1.fastq.gz	Fastqsanger.gz
	SRR33452005_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 55

Similar Datasets

bovine metagenome

Project description:URT microbiota of dairy calves

| PRJNA416929 | ENA

Project description:URT microbiome

| PRJNA758829 | ENA

Project description:URT WGS microbiome sequencing

| PRJNA1193777 | ENA

Project description:BRD Cattle URT microbiome

| PRJNA1259072 | ENA

RNA sequencing of nasal lavage samples from mock- and Streptococcus pneumoniae-infected infant and adult mice

Project description:Acute respiratory infections (ARI), which generally begin with colonization of the mucosal surfaces of the upper respiratory tract (URT), are a leading cause of morbidity and mortality with the highest rate in infants. As a common colonizer of the URT, and one of the most prevalent causes of life-threatening infections in the pediatric population, Streptococcus pneumoniae (Spn) was used as a model pathogen to investigate the effect of age during URT infection. We used RNA-sequencing to transcriptionally profile and compare the mucosal epithelia of infant and adult mice at baseline (mock-infected) and during Spn infection. Analysis of the screen revealed an age-dependent alteration of genes involved in mucosal defense mechanisms that included dampened expression of ubiquitous antimicrobial molecules and tight junction proteins in infant mice compared to adults. These results demonstrate a window of vulnerability during postnatal development when altered mucosal barrier function may facilitate bacterial colonization and invasion.

2018-10-16 | GSE116604 | GEO

Blood immune transcriptome analysis of artificially fed dairy calves and naturally suckled beef calves from birth to 7 days of age

Project description:The aim of the overall study was to investigate the development of immune competence in artificially reared dairy calves and in two breeds of naturally suckled beef calves over the first 168h of life. Dairy calves were fed 5% total body weight of colostrum, with beef calves monitored to ensure natural ingestion of colostrum. Blood samples were taken from all calves at 24h 48h 72h and 168h, and analysed for alterations to immunes genes.

2018-10-29 | GSE114432 | GEO

Analysis of blood and nasal epithelial transcriptomes to identify mechanisms associated with control of SARS-CoV-2 viral load in the upper respiratory tract

Project description:The amount of SARS-CoV-2 detected in the upper respiratory tract (URT viral load) is a key driver of transmission of infection. Current evidence suggests that mechanisms constraining URT viral load are different from those controlling lower respiratory tract viral load and disease severity. Understanding such mechanisms may help to develop treatments and vaccine strategies to reduce transmission. Combining mathematical modelling of URT viral load dynamics with transcriptome analyses we aimed to identify mechanisms controlling URT viral load. COVID-19 patients were recruited in Spain during the first wave of the pandemic. RNA sequencing of peripheral blood and targeted NanoString nCounter transcriptome analysis of nasal epithelium were performed and gene expression analysed in relation to paired URT viral load samples collected within 15 days of symptom onset. Proportions of major immune cells in blood were estimated from transcriptional data using computational differential estimation. Weighted correlation network analysis (adjusted for cell proportions) and fixed transcriptional repertoire analysis were used to identify associations with URT viral load, quantified as standard deviations (z-scores) from an expected trajectory over time.

2023-04-01 | E-MTAB-12791 | biostudies-arrayexpress

Effect of enhanced early life nutrition on anterior pituitary miRNA transcriptome in bull calves.

Project description:The aim of this study was to measure the impact of contrasting feeding regimes in the first 12 wk of life, on the molecular control of anterior pituitary tissue in bull calves. Holstein bull calves were designated to high (HI; n=15) or moderate (MOD; n=12) dietary groups, with diets designed to provoke growth rates of 1.0 and 0.5 kg/day, respectively. At 12 wk of age, all calves were euthanized, and anterior pituitary tissue harvested. RNA was extracted from the anterior pituitary and used for miRNAseq.

2025-07-09 | GSE277616 | GEO

Effect of enhanced early life nutrition on the hypothalamic arcuate nucleus transcriptome of bull calf

Project description:This study evaluated the effect of enhanced dietary intake during the early life period on hypothalamic arcuate nucleus transcriptome in bull calves. Between 2-12 weeks of age bull calves were offered either a high (HI; n=15) or moderate (MOD; n=15) plane of nutrition, with diets designed to evoke growth rates of 1.0 and 0.5 kg/day, respectively. At 12 wk of age, arcuate nucleus tissue samples were harvested from all calves and subsequently subjected to mRNAseq.

2025-04-22 | GSE278108 | GEO

Effect of enhanced early life nutrition on the anterior pituitary transcriptome of bull calf

Project description:This study evaluated the effect of enhanced dietary intake during the early life period on the anterior pituitary transcriptome in bull calves. Between 2-12 weeks of age bull calves were offered either a high (HI; n=15) or moderate (MOD; n=15) plane of nutrition, with diets designed to evoke growth rates of 1.0 and 0.5 kg/day, respectively. At 12 wk of age, anterior pituitary tissue samples were harvested from all calves and subsequently subjected to mRNAseq.

2025-07-09 | GSE278369 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data