Cryptococcus deneoformans
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA126033 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Light is a universal environmental signal perceived by many organisms, including the fungi in which light regulates both common and unique biological processes depending on the species. We conducted a whole-genome microarray analysis on the basidiomycete fungus Cryptococcus neoformans to identify light-regulated genes.
2010-04-23 | GSE21484 | GEO
Project description:Time-course microarray study of Cryptococcus neoformans var. neoformans spore germination
| PRJNA233957 | ENA
Project description:Time-course microarray study of Cryptococcus neoformans var. neoformans (JEC20xJEC21) sexual development
| PRJNA157455 | ENA
Project description:Light is a universal environmental signal perceived by many organisms, including the fungi in which light regulates both common and unique biological processes depending on the species. We conducted a whole-genome microarray analysis on the basidiomycete fungus Cryptococcus neoformans to identify light-regulated genes. Two-condition experiment, cells grown in complete darkness or exposed to white light. Six biological replicates independently grown and harvested. One replicate per array.
2010-04-23 | E-GEOD-21484 | biostudies-arrayexpress
Project description:Microarray study of the Sex Inducer Proteins in Cryptococcus neoformans var. neoformans (JEC20/21)
| PRJNA246190 | ENA
Project description:Transcriptome of Cryptococcus neoformans and Cryptococcus deneoformans
| PRJNA552283 | ENA
Project description:The goal of this study was to position all transcripts extremities in two species of Cryptococcus using TSS-Seq and QuantSeq 3' mRNA-Seq when cells are grown under different conditions. We analysed also the level of expression of each genes in the same condition using the same cell sample. All these data have spiked in using a fixed quantity of S. cereviae cells added just before DNA and RNA extraction.
2020-01-21 | GSE133695 | GEO
Project description:Cryptococcus neoformans sexual reproduction is controlled by a quorum sensing peptide
| PRJNA368839 | ENA
Project description:We measured protein translation (by ribosome profiling) and RNA levels (by polyA-enriched RNA-seq) in Cryptococcus neoformans strain H99 and Cryptococcus neoformans strain JEC21. This is the first transcriptome-wide map of translation in this species complex.
2019-06-22 | GSE133125 | GEO
Project description:Cryptococcus neoformans, an environmental opportunistic human fungal pathogen, is a causative agent for acute pulmonary infection and meningoencephalitis. Understanding the host’s response to C. neoformans infection is critical for developing effective treatment. Even though some have elucidated the host response at the transcriptome level, little is known about how it modulates its defense machinery through the proteome mechanism or how protein posttranslational modification responds to the infection. In this work, we employed a Cryptococcus murine infection model and mass spectrometry to systematically determine the proteome and acetylome statuses of two primary organs (lung and brain) in the early stage of infection. To extensively analyze the host response, we compared and integrated the proteome data to the transcriptome results. We demonstrated a significant overlap between two data sets. Critical genes, including genes involved in phagosome, lysosome, or osteoblast differentiation and platelet activation are significantly altered in protein and gene expression during infection. In the acetylome analysis, we demonstrated that lung and brain tissues differentially regulate protein acetylation during infection. The three primary groups of proteins altered in acetylation status are histones, proteins involved in glucose and fatty acid metabolism, and proteins from the immune system. These analyses provide an integrative regulation network of the host responding to C. neoformans and shed new light on understanding the host’s regulation mechanism when responding to C. neoformans.
2020-04-21 | PXD016614 | Pride