Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Streptomyces toyocaensis strain:NRRL 15009

ABSTRACT: Streptomyces toyocaensis NRRL 15009 Genome sequencing and assembly

PROVIDER: PRJNA1260954 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Multi-omic characterisation of Streptomyces hygroscopicus NRRL 30439: detailed assessment of its secondary metabolic potential

Project description:Time course intracellular proteomics of Streptomyces hygroscopicus NRRL 30439 (S. inhibens NRRL30439, CP084681) during submerged culture fermentation. Label free quantification of LC-MSMS spectra was used for protein expression profiling to support primary and secondary metabolic functionalities.

2025-06-03 | PXD030257 | Pride

Streptomyces jumonjinensis strain:NRRL 5741

Project description:Streptomyces jumonjinensis strain:NRRL 5741 Genome sequencing and assembly

| PRJNA544339 | ENA

Streptomyces toyocaensis strain:NRRL 15009

Project description:Streptomyces toyocaensis strain:NRRL 15009 Genome sequencing and assembly

| PRJNA239004 | ENA

Streptomyces chartreusis NRRL 3882

Project description:Streptomyces chartreusis NRRL 3882 Genome sequencing and assembly

| PRJNA72671 | ENA

Streptomyces chartreusis NRRL 12338

Project description:Streptomyces chartreusis NRRL 12338 Genome sequencing and assembly

| PRJNA72673 | ENA

Streptomyces rapamycinicus NRRL 5491

Project description:Streptomyces rapamycinicus NRRL 5491 Genome sequencing and assembly

| PRJNA489197 | ENA

Streptomyces caeruleatus strain:NRRL B-24802

Project description:Streptomyces caeruleatus NRRL B-24802 genome sequencing and assembly

| PRJNA299234 | ENA

Ribosome pausing at the AT-rich codons regulates the protein expression of secondary metabolite gene clusters in the Streptomyces tsukubaensis NRRL 18488

Project description:Streptomyces tsukubaensis NRRL 18488 is the preferred strain for the production of immunosuppressant agent tacrolimus (FK506). To take full advantage of its genetic potential, systematic understanding of secondary metabolism and related regulatory mechanisms is highly demanded. Here, to this end, we complete its 7.9 Mbp linear genome sequence followed by integrating with multi-omics measurements. With accurate reannotation of FK506 gene cluster, total 2,389 transcription start sites were determined by using primary transcriptome analysis. Integrated analysis of transcriptome and translatome data revealed that secondary metabolic gene clusters, especially FK506 cluster, undergo translational control with decrease in translational efficiency according to the growth. Furthermore, we demonstrated that SD motif has little correlation with ribosome pausing but AT-rich codons delay the translational elongation. Strong ribosome pausing was observed in the rare TTA codon in FK506 cluster. This comprehensive genome-scale analysis provides insight to the translational regulation of secondary metabolism in S. tsukubaensis.

2019-10-16 | GSE97637 | GEO

Streptomyces tsukubensis strain:NRRL 18488

Project description:Streptomyces tsukubensis strain:NRRL 18488 Genome sequencing

| PRJNA382016 | ENA

Streptomyces ficellus strain:NRRL 8067

Project description:Streptomyces ficellus strain:NRRL 8067 Genome sequencing

| PRJNA507930 | ENA