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Nitrogen source-driven regulation of Irpex lacteus for enhanced lignocellulose degradation and microbial protein production in wheat straw

ABSTRACT: Nitrogen source-driven regulation of Irpex lacteus for enhanced lignocellulose degradation and microbial protein production in wheat straw

PROVIDER: PRJNA1263725 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR33598533_1.fastq.gz	Fastqsanger.gz
	SRR33598533_2.fastq.gz	Fastqsanger.gz
	SRR33598534_1.fastq.gz	Fastqsanger.gz
	SRR33598534_2.fastq.gz	Fastqsanger.gz
	SRR33598535_1.fastq.gz	Fastqsanger.gz

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Nitrogen source-driven regulation of Irpex lacteus for enhanced lignocellulose degradation and microbial protein production in wheat straw

Project description:White rot fungi, such as Irpex lacteus, offer significant potential for lignocellulose degradation and protein synthesis in sustainable biofuel and animal feed production,but optimizing nitrogen sources to balance fungal growth, lignin degradation, and protein synthesis remains a critical challenge.This study investigated the effects of ammonium chloride (NH₄Cl) and sodium nitrate (NaNO₃) on I. lacteus fermentation in wheat straw, with a focus on the regulation of nitrogen source.Transcriptomic analysis revealed that NaNO₃ upregulated genes associated with nitrogen uptake and cellulose/hemicellulose degradation,while exerting less repression on key ligninolytic enzymes, such as manganese peroxidase and cytochrome P450, compared to NH₄Cl.These findings suggest that NaNO₃ enhances I. lacteus metabolism by harmonizing lignin degradation with efficient nitrogen conversion.

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