Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Prematurity and Respiratory Outcomes Program (PROP) Core Database Protocol (PROP-BioLINCC)

ABSTRACT: Prematurity and Respiratory Outcomes Program (PROP) Core Database Protocol (PROP-BioLINCC)

PROVIDER: PRJNA1281742 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Prematurity and Respiratory Outcomes Program (PROP) Core Database Protocol (PROP-BioLINCC)

Project description:Prematurity and Respiratory Outcomes Program (PROP) Core Database Protocol (PROP-BioLINCC)

| PRJNA1281741 | ENA

Fern Database

Project description:Fern Database

| PRJEB72795 | ENA

Prematurity alters the progenitor cell program of the upper respiratory tract of neonates

Project description:The impact of prematurity in human development and neonatal diseases, such as bronchopulmonary dysplasia, have been widely reported. However, little is known about the effects of prematurity on the programs of stem cell self-renewal and differentiation of the upper respiratory epithelium, key for adaptation to neonatal life. Here we developed a minimally invasive methodology for isolation and functional analysis of basal cells from nasopharyngeal (NP) aspirates of newborn infants in organotypic cultures to address this issue. We show that pre-term NP progenitors have a markedly distinct molecular signature of a prematurity-associated abnormal program of proliferation and mitochondria quality control compared to term cells. Prematurity differentially inhibited mitochondria respiration and, although it did not prevent cell differentiation it was later associated with differences in mitochondrial and innate immunity-related genes. Together these differences suggested increased sensitivity of pre-term progenitors to environmental stressors compared to term under non-homeostatic conditions.

2021-01-07 | GSE164358 | GEO

The NIH Human Pluripotent Stem Cell Database (Affymetrix, mRNA)

Project description:To broaden the appeal of the NIH Stem Cell Database, we analyzed a subset of undifferentiated human embryonic stem cell lines (5 lines in duplicate) on the Affymetrix platform. One standard culture protocol was used in conjunction with rigorous quality control. Expanded description of methods used and are available at: http://stemcelldb.nih.gov.

2012-10-31 | GSE33789 | GEO

WGA protocol optimization

Project description:WGA protocol optimization

| PRJEB34940 | ENA

Tissue Procurement Protocol

Project description:Tissue Procurement Protocol

| PRJNA819531 | ENA

Circular RNA Profiling in Peripheral Blood Mononuclear Cells from Retinopathy of Prematurity

Project description:To reveal the altered expression profiles of circular RNAs (circRNAs) in the peripheral blood mononuclear cells (PBMCs) of patients with retinopathy of prematurity (ROP), microarray analysis was conducted in the samples from ROP patients and controls.

2022-08-10 | GSE204780 | GEO

Sample preparation procedure for mass spectrometric analysis of plant histones

Project description:The protocol for preparing samples of plant histones prior to LC-MS/MS analysis was established, using a filter-aided sample preparation (FASP) technique to remove natural contaminants and chemical additives incompatible with MS-based procedures. The protocol consists of nuclei isolation, histone extraction into acidic solvent, protein propionylation and on-membrane digestion, then peptide propionylation in solution. Two variants of the derivatization protocol, in-solution propionylation in the vial (PROP-in-SOL) and propionylation on the filter unit (PROP-on-FILTER), were compared by efficiency of the labeling and by abundance of identified histone peptide forms.

2018-09-20 | PXD010102 | Pride

General Surgical Outcomes Quality Improvement Database (UH-SOCRATES)

Project description:A database has been established to track the outcomes of all cases performed in the University Hospitals Department of Surgery in an effort to improve quality of surgical performance and case management. Specifically, the purpose of the database will be used as a quality improvement tool for analyzing process and outcome measures and to accurately track cases performed by surgeons.

| 2051182 | ecrin-mdr-crc

EcoToxChip 2016 LSARP RNASeq database

Project description:EcoToxChip 2016 LSARP RNASeq database

| PRJNA1000951 | ENA