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Transcriptome sequencing data analysis of Bacillus subtilis NCIB 3610 treated with DMSO and AQCA

ABSTRACT: Transcriptome sequencing data analysis of Bacillus subtilis NCIB 3610 treated with DMSO and AQCA

PROVIDER: PRJNA1285989 | ENA |

REPOSITORIES: ENA

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Transcriptome sequencing data analysis of Bacillus subtilis NCIB 3610 treated with DMSO and AQCA

Project description:In our study, we discovered that AQCA (Anthraquinone-2-carboxylic acid) effectively degrades Bacillus subtilis NCIB 3610 biofilms, a finding of significant research importance. To investigate the underlying mechanisms, we performed transcriptome sequencing of wild-type biofilms treated with either DMSO (control) or AQCA. Statistical analysis of gene expression (P < 0.05) revealed that AQCA treatment led to significant changes: 184 genes were upregulated, while 503 genes were downregulated by at least twofold compared to the DMSO control group.

2025-07-08 | GSE301691 | GEO

Bacillus subtilis strain:NCIB 3610

Project description:Bacillus subtilis NCIB 3610

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Bacillus subtilis strain:NCIB 3610 | isolate:NCIB 3610

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