Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Ornithorhynchus anatinus

ABSTRACT: 6X whole genome shotgun assembly by Washington University Genome Sequencing Center

PROVIDER: PRJNA12885 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR000910.fastq.gz	Fastqsanger.gz
	SRR000911.fastq.gz	Fastqsanger.gz
	SRR000912.fastq.gz	Fastqsanger.gz
	SRR065183.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 53

Similar Datasets

Ornithorhynchus anatinus

Project description:Ornithorhynchus anatinus Genome sequencing and assembly

| PRJNA433451 | ENA

Ornithorhynchus anatinus

Project description:Ornithorhynchus anatinus Genome sequencing

| PRJNA186438 | ENA

Ornithorhynchus anatinus

Project description:Targeted genome sequencing of Ornithorhynchus anatinus

| PRJNA13682 | ENA

Ornithorhynchus anatinus

Project description:The mitochondrial genome of the duck-billed platypus has been sequenced

| PRJNA10802 | ENA

Characterization of the Mel1c melatoninergic receptor in platypus (Ornithorhynchus anatinus).

Project description:Melatonin is a neurohormone produced in both animals and plants. It binds at least three G-protein-coupled receptors: MT1 and MT2, and Mel1cGPR. Mammalian GPR50 evolved from the reptilian/avian Mel1c and lost its capacity to bind melatonin in all the therian mammal species that have been tested. In order to determine if binding is lost in the oldest surviving mammalian lineage of monotremes we investigated whether the melatonin receptor has the ability to bind melatonin in the platypus (Ornithorhynchus anatinus), and evaluated its pharmacological profile. Sequence and phylogenetic analysis showed that platypus has in fact retained the ancestral Mel1c and has the capacity to bind melatonin similar to other mammalian melatonin receptors (MT1 and MT2), with an affinity in the 1 nM range. We also investigated the binding of a set of melatoninergic ligands used previously to characterize the molecular pharmacology of the melatonin receptors from sheep, rats, mice, and humans and found that the general profiles of these compounds make Mel1c resemble human MT1 more than MT2. This work shows that the loss of GPR50 binding evolved after the divergence of monotremes less than 190MYA in therian mammals.

| S-EPMC5846726 | biostudies-literature

Ornithorhynchus anatinus

Project description:Ornithorhynchus anatinus, or duck-billed platypus, is a primitive egg-laying mammal

| PRJNA10803 | ENA

Ornithorhynchus anatinus

Project description:Platypus fibroblast and ovary transcriptomes

| PRJNA152927 | ENA

Ornithorhynchus anatinus

Project description:Proteome

| PRJNA898817 | ENA

Taeniopygia guttata

Project description:Taeniopygia guttata 6X whole genome shotgun assembly