Project description:This dataset contains data-independent acquisition (DIA) proteomics data generated from K562 human leukemia cells treated with coffee extract or vehicle control. Quantitative proteomic analysis was performed to investigate molecular mechanisms underlying coffee-induced epigenetic remodeling. The proteomics dataset was integrated with histone modification profiling, ChIP-seq and RNA-seq analyses to characterize pathways associated with histone acetylation and MYC transcriptional regulation.
2026-07-08 | PXD080702 | JPOST Repository
Project description:evaluating a melon germplasm collection
| PRJNA1243015 | ENA
Project description:Genome Skimming of Fragaria germplasm collection "Professor Staudt Collection"
| PRJNA741339 | ENA
Project description:Sequence variation in Erianthus germplasm collection
Project description:Single cell RNA-seq was conducted on embryonic brains from wild-type CD1 mice at embryonic day 15.5 following The Illumina® Bio-Rad® SureCell Single-Cell RNA Sequencing workflow. Four cell captures and sequencing runs were conducted with four to eight fetal brains used for each collection. For each brain, the cerebral cortex was dissected and collected (although ventral forebrain structures, especially the gonglionic eminence may be mixed in due to difficulty in dissection).
Project description:The present study was conducted to evaluate the effects of the intake of three types of coffee (caffeinated, decaffeinated, and green unroasted coffee) on the livers of C57BL/6J mice fed a high-fat diet, and to extensively elucidate the physiological responses to coffee intake by analysing the findings obtained from a comprehensive transcriptomic analysis using DNA microarrays. The present study was conducted to evaluate the effects of the intake of three types of coffee (caffeinated, decaffeinated, and green unroasted coffee) on the livers of C57BL/6J mice fed a high-fat diet, and to extensively elucidate the physiological responses to coffee intake by analysing the findings obtained from a comprehensive transcriptomic analysis using DNA microarrays.
Project description:Our experiments showed that long-term coffee or green tea(GTE) extract supplementation( from 3 months old to 12 months old) ameliorates age-related hearing loss (ARHL) in mice. Then we explored the possible underlying mechanisms through comparing the cochlear transcriptome profiling (RNA-seq) of the coffee or GTE treated mice to the control mice.
