Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Staphylococcus aureus, Corynebacterium striatum

ABSTRACT: CS: Corynebacterium striatumSA: Staphylococcus aureusSA-CS: Co-cultured Staphylococcus aureus and Corynebacterium striatum Raw sequence reads

PROVIDER: PRJNA1313462 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Mechanism of Corynebacterium striatum-mediated inhibition of Staphylococcus aureus-induced epithelial barrier injury and inflammation activation in chronic rhinosinusitis

Project description:Microbes are an important trigger of chronic rhinosinusitis (CRS). Staphylococcus aureus is a CRS-related pathogen that disrupts the epithelial barrier and activates mucosal inflammation. Given the ineffectiveness of antimicrobial therapy in CRS, we explored a potential treatment based on the interaction of bacteria within the dysbiotic microenvironment of the nasal mucosa. Microbiome analyses of clinical isolates from CRS patients and healthy controls were employed to identify Corynebacterium striatum as a potential inhibitor of pathogenic S. aureus. A co-infection culture model using human nasal epithelial cells (hNECs) was constructed to investigate the inhibition of S. aureus-induced disruption of the host epithelium by C. striatum. Further analysis of the inhibition of S. aureus by C. striatum was carried out using a bacteria co-culture model.

2026-03-01 | GSE284409 | GEO

Mechanism of Corynebacterium striatum-mediated inhibition of Staphylococcus aureus-induced epithelial barrier injury and inflammation activation in chronic rhinosinusitis [RNA-Seq]

2026-03-01 | GSE284820 | GEO

Corynebacterium striatum

Project description:Corynebacterium striatum Genome sequencing

| PRJNA825744 | ENA

Corynebacterium striatum BM4687

Project description:Corynebacterium striatum BM4687

| PRJEB8812 | ENA

Corynebacterium striatum

Project description:Corynebacterium striatum Raw sequence reads

| PRJNA512256 | ENA