Project description:This SuperSeries is composed of the following subset Series: GSE25068: PcG/TrxG profiling of differentially aged adipose-derived mesenchymal stem cells GSE25069: Whole-genome microarray of long-term cultured adipose derived mesenchymal stem cells from differentially-aged mice GSE25679: microRNA profiling of mesenchymal stem cells from adipose tissue of differentially aged mice Refer to individual Series
Project description:The microarray reported here is part of a study aimed to investigate whether the gene expression of Polycomb, Trithorax and interacting molecule might be related to differet states of differentialtive potential. In particular, the dataset herein is a whole-genome microarray profiling of long-term (20th passage) cultured mesenchymal stem cells isolated from the inguinal fat pad of mice of differentially aged mice. Whole genome transcriptional profile of mesenchymal stem cells isolated from FVB mice of 1 (n=3) or 12 (n=3) months of age.
Project description:The microarray reported here is part of a study aimed to investigate whether the gene expression profile of Polycomb, Trithorax and interacting molecules (collectively referred to PcG/TrxG genes) might be related to different states of differentiative potential. In particular , this microarray profiles the expression of PcG/TrxG genes in adipose-derived mesenchymal stem cells isolated from the inguinal fat depot of mice of different age. MSC have been isolated from the inguinal fat pad of FVB mice aged 1, 3, 6, 12 or 24 months.
