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Omics score: 0

Mus musculus

ABSTRACT: Induction of trophoblast stem cells from embryonic stem cells by forced repression of Oct3/4.

OTHER RELATED OMICS DATASETS IN: E-GEOD-28451

PROVIDER: PRJNA143233 | ENA |

REPOSITORIES: ENA

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Induction of trophoblast stem cells from embryonic stem cells by forced repression of Oct3/4.

2013-10-17 | GSE28452 | GEO

Induction of trophoblast stem cells from embryonic stem cells by forced repression of Oct3/4.

Project description:To characterize the transdifferentiation of embryonic stem (ES) cells into trophoblast stem (TS) cells triggered by forced repression of Oct3/4, we performed whole-genome expression analysis after tetracycline (Tet)-induced knockout of Oct3/4. A Tet-inducible Oct3/4 knockout ES cell line ZHBTc4 was treated with Tet for 4 days in the presence of FGF4 and mouse embryonic fibroblasts (MEFs). A total of 15 samples from Day 0 to Day 4 were analyzed in three biological replicates.

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