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Heterocephalus glaber

ABSTRACT: Transcriptome sequencing of naked mole rat, Heterocephalus glaber

PROVIDER: PRJNA143625 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR306394_1.fastq.gz	Fastqsanger.gz
	SRR306394_2.fastq.gz	Fastqsanger.gz
	SRR306395_1.fastq.gz	Fastqsanger.gz
	SRR306395_2.fastq.gz	Fastqsanger.gz
	SRR306396_1.fastq.gz	Fastqsanger.gz

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Transcriptome sequencing of naked mole rat, Heterocephalus glaber

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Transcriptome sequencing of naked mole rat, Heterocephalus glaber

Project description:Deep sequencing of mRNA from naked mole rat Analysis of ploy(A)+ RNA of different specimens: brain, kidney, liver from new born , 4 years old , 20 years old and 4 years old hypoxia-exposed naked mole rat

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RNA sequencing reveals differential expression of mitochondrial and oxidation reduction genes in the long-lived naked mole-rat when compared to mice.

Project description:The goal was to find genes which are differentially expressed between the naked mole-rat (Heterocephalus glaber) and the wild-type mice liver tissue. The genes which are most differentially expressed may provide a clue for the remarkable differences between naked mole-rat and mouse in terms of longevity, cancer resistance and adaptation to subterranean environments.

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Heterocephalus glaber

Project description:Heterocephalus glaber genome sequencing

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RNA sequencing reveals differential expression of mitochondrial and oxidation reduction genes in the long-lived naked mole-rat when compared to mice.

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Methylation studies in mole rats. Part 2

Project description:An Infinium microarray platform (GPL28271, HorvathMammalMethylChip40) was used to generate DNA methylation data from many tissues of 3 species of mole rats: Cape mole rat (Georychus capensis), Damaraland mole rat (Cryptomys damarensis), Naked mole rat (Heterocephalus glaber). We generated DNA methylation data from n=94 tissues from 3 species: Cryptomys damarensis (n=10), Georychus capensis (n=6), Heterocephalus glaber (n=78). All tissues ewere obtained from frozen tissue collection that were euthanized for other studies. Kidney (n=6), liver (n=61), skin (n=27). The tissues used in this study were obtained from post-mortem specimens from animals free from disease in compliance. Sample collection was from post-mortem material. Tissue samples were snap frozen in liquid nitrogen following dissection and transferred for storage at -80ºC. Genomic DNA was extracted using Qiagen DNeasy Blood and Tissue kit and quantified using Nanodrop and Qubit.als

2021-10-18 | GSE174778 | GEO

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