Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Caenorhabditis elegans

ABSTRACT: MicroRNAs induced during response to stress in C. elegans

PROVIDER: PRJNA152255 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR404123.fastq.gz	Fastqsanger.gz
	SRR404124.fastq.gz	Fastqsanger.gz
	SRR404125.fastq.gz	Fastqsanger.gz
	SRR404126.fastq.gz	Fastqsanger.gz
	SRR404127.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 8

Similar Datasets

Caenorhabditis elegans

Project description:SKN-1-dependent oxidative stress response in C. elegans

| PRJNA102949 | ENA

Caenorhabditis elegans

Project description:MicroRNA mir-34 provides robustness to environmental stress response in C. elegans

| PRJNA307238 | ENA

Role of microRNAs in regulating the DNA damage response to ionizing radiation in Caenorhabditis elegans

Project description:microRNAs fine-tune the regulation of numerous biological processes by mediating gene expression post-transcriptionally. Mature miRNAs associate with argonaute (AGO) proteins to form the RNA-induced silencing complex (RISC) that binds to and blocks translation of target mRNAs. In our study, we address the function of miRNAs in regulating DNA damage responses in-vivo, by exploiting the nematode model organism Caenorhabditis elegans. Using next-generation sequencing, we obtained miRNA expression profiles of WT worms as well as mutants harboring a loss-of-function deletion of the C. elegans AGO gene alg-2 that display abnormal cell death in response to genotoxic stress. 2.5 hours after exposure to ionizing irradiation, the miRNA transcriptomes of both WT and alg-2(ok304) mutant worms were only mildly altered in comparison to their respective untreated controls. However, irrespective of treatment, alg-2(ok304) mutants exhibited noticeable dysregulation of several miRNA families with known physiological functions. Reduced levels of some of these miRNAs might explain the abnormal DNA damage response of alg-2-deficient C. elegans.

2023-01-02 | GSE124606 | GEO

Caenorhabditis elegans

Project description:Tocotrienol Rich Fraction (TRF) Modulates Genes Expression in Oxidative Stress-Induced Caenorhabditis elegans

| PRJNA393168 | ENA

Caenorhabditis elegans

Project description:Deep sequencing of C. elegans microRNAs under starvation conditions

| PRJNA280742 | ENA

Caenorhabditis elegans

Project description:C. elegans heat stress time course

| PRJNA87983 | ENA

Caenorhabditis elegans

Project description:Influence of p38 MAPK (PMK-1) on the heat stress response of C. elegans

| PRJNA176153 | ENA

Caenorhabditis elegans

Project description:Insulin-like Signaling Determines Survival During Stress via Post Transcriptional Mechanisms in C. elegans.

| PRJNA127629 | ENA

Caenorhabditis elegans infected with Staphylococcus aureus

Project description:Young adult fer-15;fem-1 Caenorhabditis elegans were infected with Staphylococcus aureus for 8 h to determine the transcriptional host response to Staphylococcus aureus. Analysis of differential gene expression in C. elegans young adults exposed to two different bacteria: E. coli strain OP50 (control), wild-type Staphylococcus aureus RN6390. Samples were analyzed at 8 hours after exposure to the different bacteria. These studies identified C. elegans genes induced by pathogen infection. Keywords: response to pathogen infection, innate immunity, host-pathogen interactions

2010-06-12 | GSE21819 | GEO

Caenorhabditis elegans

Project description:piRNA-induced silencing in C. elegans

| PRJNA612883 | ENA