Schizosaccharomyces pombe
Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: GSE36214
PROVIDER: PRJNA155805 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Puf3 is a RNA-binding protein, a member of the conserved Puf-protein family. Combining different functional genomics data, we have analyzed the role of Puf3 in post-transcriptional gene regulation in S. pombe. We present data on Puf3 interacting proteins and regulatory mRNA targets.
2022-03-23 | PXD006318 | Pride
Project description:RNA expression profiling for Paf1 complex mutant strains [mRNA]
| PRJNA254526 | ENA
Project description:RNA expression profiling for Paf1 complex mutant strains [miRNA]
| PRJNA254525 | ENA
Project description:Clr4/Suv39 and RNA quality control factors cooperate to trigger RNAi and suppress antisense RNA (expression)
| PRJNA142035 | ENA
Project description:Untimely expression of gametogenic genes in vegetative cells causes uniparental disomy (RNA-seq)
| PRJNA309328 | ENA
Project description:Small RNA expression in swi6 mutants or dcr1 delta fission yeast Schizosaccharomyces pombe
| PRJNA183638 | ENA
Project description:Cdk11-Cyclin L controls the assembly of the RNA polymerase II Mediator [expression]
| PRJNA165855 | ENA
Project description:Individual letters of the RNA polymerase II CTD code govern distinct gene expression programs in fission yeast
| PRJNA227531 | ENA
Project description:Eukaryotic telomeres are transcribed into telomeric repeat-containing RNA (TERRA). Telomeric transcription has been documented in mammals, birds, zebra fish, plants and budding yeast. Here we show that the chromosome ends of Schizosaccharomyces pombe produce distinct RNA species. As with budding yeast and mammals, S. pombe contains G-rich TERRA molecules and subtelomeric RNA species transcribed in the opposite direction of TERRA (ARRET). Moreover, fission yeast chromosome ends produce two novel RNA species: C-rich telomeric repeat-containing transcripts (ARIA) and subtelomeric transcripts complementary to ARRET (αARRET). RNA polymerase II (RNAPII) associates with pombe chromosome ends in vivo and the telomeric factor Rap1 negatively regulates this association, as well as the cellular accumulation of RNA emanating from chromosome ends. We also show that the RNAPII subunit Rpb7 and the non-canonical poly(A) polymerases Cid12 and Cid14 are involved in the regulation of TERRA, ARIA, ARRET and αARRET transcripts. We confirm the evolutionary conservation of telomere transcription, and reveal intriguing similarities and differences in the composition and regulation of telomeric transcripts among model organisms.
| S-EPMC3326308 | biostudies-literature
Project description:BackgroundConjugation of the ubiquitin-like modifier Nedd8 to cullins is critical for the function of SCF-type ubiquitin ligases and thus facilitates ubiquitin conjugation and ultimately degradation of SCF substrates, including several cell cycle regulators. Like ubiquitin, Nedd8 is produced as a precursor that must first be processed before it becomes active. In Saccharomyces cerevisiae this is carried out exclusively by the enzyme Yuh1.ResultsHere we show that in the fission yeast, Schizosaccharomyces pombe, the Yuh1 orthologue, Uch1, is not the sole Nedd8 processing enzyme. Instead it appears that deubiquitylating enzymes can efficiently process the Nedd8 precursor in vivo.ConclusionsSeveral enzymes contribute to Nedd8 precursor processing including a number of deubiquitylating enzymes.
| S-EPMC3602023 | biostudies-literature