Project description:SNP array data from 12 childhood adrenocortical tumors (ACT) were used to identify recurrent chromosome rearrangements and candidate driver genes.
Project description:SNP array data from 12 childhood adrenocortical tumors (ACT) were used to identify recurrent chromosome rearrangements and candidate driver genes. 12 childhood ACT were analyzed with Illumina Human610-Quad v1.0 BeadChips.
Project description:SNP array data from 13 Brazilian childhood adrenocortical tumors (ACTs) were analyzed to detect recurrent copy number changes and highlight potential candidate driver genes.
Project description:SNP array data from 13 Brazilian childhood adrenocortical tumors (ACTs) were analyzed to detect recurrent copy number changes and highlight potential candidate driver genes. 13 childhood ACT were analyzed with Illumina HumanCNV370-Duo v1.0 chips. Paired normal blood samples from 6 patients were analyzed with Illumina HumanCNV370-Quad v3.0 chips.
Project description:Adrenocortical tumors in children are rare, but 10-15 times more incident in Southern Brazil than in the rest of the world. However, reliable biomarkers capable of establishing a well-defined prognostic correlation or predicting relapse risk of the disease are still challenging. Herein, we aimed to compare the expression profiles of pediatric adrenocortical tumors of patients with favorable and unfavorable clinical outcomes.
