Project description:We report the transcriptomic analysis of the response of P. aeruginosa AG1 to Ciprofloxacin to identify molecular determinants related to its tolerance to the antibiotic and the enriched pathways along time
Project description:Here, we investigated whether the ag1 gene, which plays a key role in regeneration in fish and amphibians and was lost in amniotes, could enhance skin wound healing in mice. We generated transgenic mice with inducible expression of the Xenopus laevis ag1 gene in the skin and compared wound healing dynamics between induced and non-induced groups. Induction of ag1 resulted in approximately 20% faster wound closure. Transcriptomic analysis revealed enhanced activation of multpathways involved in wound repair
Project description:RNA-seq analysis of Pseudomonas sp OST1909 exposed to various preparations of naphthenic acids samples led to the identiifcation of many NA-induced genes.
