Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Francisella tularensis subsp. tularensis SCHU S4

ABSTRACT: Francisella tularensis Schu4 gene expression during infection of mouse spleen

PROVIDER: PRJNA171923 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Francisella tularensis subsp. tularensis SCHU S4

Project description:Francisella tularensis tularensis Schu_S4 Genome sequencing

| PRJNA239340 | ENA

Francisella tularensis subsp. tularensis SCHU S4

Project description:Genome Sequencing of 3 Select Agent-Exempt Strains of Francisella tularensis subsp. tularensis SCHU S4

| PRJNA341509 | ENA

Gene expression in F. tularensis subsp. tularensis SCHU P0, P5, and P9 strains.

Project description:The microarray analysis of Francisella tularensis subsp. tularensis strains SCHU P9 (virulent) and SCHU P0/P5 (attenuated) revealed significant differences in gene expression. The results showed that 19 genes were upregulated in the virulent SCHU P9 strain, while two genes, including ftt_0965c, were significantly downregulated

2024-12-31 | GSE274776 | GEO

Francisella tularensis subsp. tularensis SCHU S4

Project description:virulence determinants of Francisella tularensis revealed by transcriptional profiling inside macrophages

| PRJNA113073 | ENA

Francisella tularensis subsp. tularensis strain:SCHU-P0, SCHU-P5, SCHU-P9

Project description:Francisella tularensis subsp. tularensis multi-isolate project

| PRJDA51189 | ENA

Francisella tularensis subsp. tularensis str. SCHU S4 substr. SL

Project description:Francisella tularensis subsp. tularensis str. SCHU S4 substr. SL Genome sequencing and assembly

| PRJNA217351 | ENA

Francisella tularensis subsp. tularensis str. SCHU S4 substr. FSC237

Project description:Francisella tularensis subsp. tularensis str. SCHU S4 substr. FSC237 Genome sequencing and assembly

| PRJNA217352 | ENA

In vivo screen of Francisella tularensis subsp. novicida mutants in sequence defined transposon library

Project description:We used an inhalation mouse model of infection to query a collection of 2149 mutants in a Francisella tularensis subsp. novicida background for genes required for growth, survival and systemic dissemination. A microarray-based genome-wide negative selection screen (Microarray tracking of transposon mutants = MATT) allowed us to monitor the behavior of transposon insertions in 1371 unique genes. Interestingly most of these genes persisted in lung and colonized liver and spleen. We found 44 (35%) genes negatively selected in lung and 81 (65%) genes negatively selected in liver and/or spleen. If negative selection in lung occurred, the attenuated mutants in general persisted at 24h after infection, disseminated to liver and/or spleen and appeared to be lost in lung after 48 to 72h of infection. These genes with a strong phenotype in lung but also potential for dissemination might be attractive vaccine or drug candidates. Keywords: Genome-Wide Negative Selection Screen

2008-12-31 | GSE11297 | GEO

Francisella tularensis subsp. tularensis str. SCHU S4 substr. NR-10492

Project description:Francisella tularensis subsp. tularensis str. SCHU S4 substr. NR-10492 Genome sequencing and assembly

| PRJNA217349 | ENA

Francisella tularensis subsp. tularensis str. SCHU S4 substr. NR-28534

Project description:Francisella tularensis subsp. tularensis str. SCHU S4 substr. NR-28534 Genome sequencing and assembly

| PRJNA217348 | ENA