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Blastomyces dermatitidis ATCC 26199

ABSTRACT: Blastomyces dermatitidis ATCC 26199 Transcriptome or Gene expression

PROVIDER: PRJNA185598 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR1130270_1.fastq.gz	Fastqsanger.gz
	SRR1130270_2.fastq.gz	Fastqsanger.gz
	SRR1130290_1.fastq.gz	Fastqsanger.gz
	SRR1130290_2.fastq.gz	Fastqsanger.gz
	SRR1130300_1.fastq.gz	Fastqsanger.gz

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Project description:The goal of this study was to capture the transcriptional response regulated by the GATA transcription factor encoded by SREB during the first 48-hours of the temperature-dependent shift from yeast (37oC) to mycelia (22oC). Gene expression microarrays were used to compare an SREB null mutant (SREBΔ) to an isogenic wild type strain (ATCC 26199). SREB null mutants fail to fully complete the conversion from yeast to sporulating mycelia after a drop in temperature from 37oC to 22oC, and under iron-replete conditions cannot properly repress siderophore biosynthesis. Deletion of SREB in ATCC 26199 produced SREBΔ. The isogenic wild-type strain is ATCC 26199.

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| S-EPMC11616655 | biostudies-literature

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