Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Trichophyton interdigitale MR816

ABSTRACT: sequencing of Trichophyton

PROVIDER: PRJNA186835 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR825154_1.fastq.gz	Fastqsanger.gz
	SRR825154_2.fastq.gz	Fastqsanger.gz
	SRR825155_1.fastq.gz	Fastqsanger.gz
	SRR825155_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 5

Similar Datasets

Trichophyton interdigitale

Project description:Trichophyton interdigitale overview

| PRJNA622627 | ENA

Trichophyton interdigitale H6 strain:H6

Project description:sequencing of Trichophyton

| PRJNA186827 | ENA

Trichophyton interdigitale strain:IGIB-BK-CI04

Project description:Trichophyton interdigitale strain:IGIB-BK-CI04 Genome sequencing and assembly

| PRJNA923504 | ENA

Trichophyton interdigitale strain:UCMS-IGIB-CI12

Project description:Trichophyton interdigitale strain:UCMS-IGIB-CI12 Genome sequencing and assembly

| PRJNA604098 | ENA

Trichophyton interdigitale strain:UCMS-IGIB-CI14

Project description:Trichophyton interdigitale strain:UCMS-IGIB-CI14 Genome sequencing and assembly

| PRJNA604102 | ENA

Trichophyton interdigitale strain:UCMS-IGIB-CI11

Project description:Trichophyton interdigitale strain:UCMS-IGIB-CI11 Genome sequencing and assembly

| PRJNA599558 | ENA

Differential analysis of transcriptome of different Trichophyton mentagrophytes strains

Project description:The CDR1 gene of Trichophyton beardii was knocked out and replenished by ATMT technology. The effect of CDR1 gene on the gene expression profile of Trichophyton beardii was studied by high-throughput sequencing

2025-05-06 | GSE202357 | GEO

Differential analysis of transcriptome of Trichophyton mentagrophytes treated with Trichoderma

Project description:Under the action of Trichophyton 1000 UG / ml, the colony of Trichophyton mentagrophyte was completely inhibited. The spore number and germination rate of Trichophyton mentagrophyte under the action of 100ug / ml and 10ug / ml were significantly lower than those in the control group. Under the action of Trichophyton, the mitochondria in the mycelium of Trichophyton mentagrophyte were cleaved. Under the action of trichomycin, the related genes in mitochondria decreased significantly. This showed that mitochondria were obviously damaged during trichomycin treatment. It is speculated that Trichophyton can cause mitochondrial damage and reduce the efficiency of respiratory chain, but Trichophyton can synthesize enough ATP by regulating related ATP synthase to resist the invasive effect caused by Trichophyton stimulation.

2024-12-02 | GSE190018 | GEO

Tinea faciei on the right eyebrow caused by Trichophyton interdigitale.

Project description:Tinea faciei is a relatively uncommon dermatophyte infection entailing atypical clinical symptoms, usually misdiagnosed and treated with corticosteroids. The authors describe a case of tinea faciei on the right eyebrow caused by Trichophyton interdigitale. The patient was an 18-year-old girl, who had an inflammatory plaque with a scaly, pustular surface on the right eyebrow and upper eyelid, which had persisted for over 1 month. She was once misdiagnosed as having eczema and was treated using corticosteroid cream. A diagnosis of tinea faciei was made based on direct microscopy and culture. The sequencing of the nuclear ribosomal ITS region and β-tubulin gene of the isolate established its T. interdigitale lineage. The patient was cured by treatment with systemic terbinafine in combination with topical application of 1% naftifine-0.25% ketaconazole cream for 2 weeks.

| S-EPMC5193201 | biostudies-literature

Mutation in the Squalene Epoxidase Gene of Trichophyton interdigitale and Trichophyton rubrum Associated with Allylamine Resistance.

Project description:Dermatophytosis, the commonest superficial fungal infection, has gained recent attention due to its change of epidemiology and treatment failures. Despite the availability of several agents effective against dermatophytes, the incidences of chronic infection, reinfection, and treatment failures are on the rise. Trichophyton rubrum and Trichophyton interdigitale are the two species most frequently identified among clinical isolates in India. Consecutive patients (n = 195) with suspected dermatophytosis during the second half of 2014 were included in this study. Patients were categorized into relapse and new cases according to standard definitions. Antifungal susceptibility testing of the isolated Trichophyton species (n = 127) was carried out with 12 antifungal agents: fluconazole, voriconazole, itraconazole, ketoconazole, sertaconazole, clotrimazole, terbinafine, naftifine, amorolfine, ciclopirox olamine, griseofulvin, and luliconazole. The squalene epoxidase gene was evaluated for mutation (if any) in 15 T. interdigitale and 5 T. rubrum isolates exhibiting high MICs for terbinafine. A T1189C mutation was observed in four T. interdigitale and two T. rubrum isolates. This transition leads to the change of phenylalanine to leucine in the 397th position of the squalene epoxidase enzyme. In homology modeling the mutant residue was smaller than the wild type and positioned in the dominant site of squalene epoxidase during drug interaction, which may lead to a failure to block the ergosterol biosynthesis pathway by the antifungal drug.

| S-EPMC5923174 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data