Project description:miRNA expression analyses of Tif1b-deficient hematopoietic stem cells (HSCs). Tif1b loss leds to rapid depletion of HSCs. Expression analyses provide insight into the role of Tif1b in the maitenance of HSC.
Project description:miRNA expression analyses of Tif1b-deficient hematopoietic stem cells (HSCs). Tif1b loss leds to rapid depletion of HSCs. Expression analyses provide insight into the role of Tif1b in the maitenance of HSC. HSCs (c-Kit+ Sca1+ Lineage- ) are sorted from adult bone marrow and are subjected into microarray analyses.
Project description:Gene expression analyses of Tif1b-deficient hematopoietic stem cells (HSCs). Tif1b loss leads to rapid depletion of HSCs. Expression analyses provide insight into the role of Tif1b in the maitenance of HSC.
Project description:Gene expression analyses of Tif1b-deficient hematopoietic stem cells (HSCs). Tif1b loss leads to rapid depletion of HSCs. Expression analyses provide insight into the role of Tif1b in the maitenance of HSC. HSCs (c-Kit+ Sca1+ Lineage- ) are sorted from fetal liver or adult bone marrow and are subjected into microarray analyses.
Project description:The transcriptome of Ctrl and Vitamin A-deficient longterm hematopoietic stem cells (LT-HSC) and multipotant progenitors (MPP3/4) was assessed by RNAseq.