Bos taurus
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA227763 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Transcriptional profiling of blood B cells from bovine leukemia virus-infected cattle comparing IgMhigh B cells with IgMlow B cells. Goal was to estimate the difference of cellular function in both subset. Two-condition experiment, IgMhigh B cells vs. IgMlow B cells from three bovine leukemia virus-infected cattle.
2014-04-01 | E-GEOD-52388 | biostudies-arrayexpress
Project description:Extracellular vesicles (EVs) are key mediators of intercellular communication, and often play critical roles in host-parasite interactions by facilitating parasite’s physiology and pathogenesis. Theileria annulata, an apicomplexan parasite, induces profound changes in host cells, leading to uncontrolled proliferation, apoptosis resistance, and increased invasiveness. In this study, we performed the comprehensive proteomic and small RNA analysis of EVs isolated from a T. annulata Kashi isolate-infected bovine lymphocyte cell line (TaXJS), B cell line (TaBC), dendritic cell line (TaDC), and from the sera of cattle before and after infection. Our label-free LC-MS/MS proteomics identified 2580 proteins, while small RNA sequencing revealed 6635 miRNAs associated with parasite development, host invasion, and immune evasion. Functional enrichment analyses recognized vesicular components involved in key pathways of the parasite-host such as ECM-receptor interaction, oxidative phosphorylation, and proton transport. These findings highlight the potential of Theileria-derived EVs in modulating host responses and their potential as therapeutic and vaccine targets.
2025-09-29 | PXD056906 | Pride
Project description:Bovine trophoblasts: control vs. infected with Brucella abortus
| PRJNA105583 | ENA
Project description:Transcriptional profiling of blood B cells from bovine leukemia virus-infected cattle comparing IgMhigh B cells with IgMlow B cells. Goal was to estimate the difference of cellular function in both subset.
2014-04-01 | GSE52388 | GEO
Project description:Identification of novel, highly expressed retroviral microRNAs in cells infected by bovine foamy virus
| PRJNA280497 | ENA
Project description:Differentially-expressed miRNAs in MDBK cells infected with bovine viral diarrhea virus compared to MDBK cells
| PRJNA260603 | ENA
Project description:Effect of bovine viral diarrhoea virus infection in Madin-Darby bovine kidney cells
| PRJNA87705 | ENA
Project description:MicroRNA expression in bovine satellite cells at 6th day of in vitro differentiation - myotubes (Hereford & Limousin vs Holstein-Freisian cattle)
| PRJNA297871 | ENA
Project description:Whole blood gene expression profiling in preclinical and clinical cattle infected with atypical bovine spongiform encephalopathy.
| PRJNA284398 | ENA