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Homo sapiens

ABSTRACT: Characterization of the Merkel cell carcinoma miRNome

PROVIDER: PRJNA232473 | ENA |

REPOSITORIES: ENA

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Dataset's files

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			Action	DRS
	SRR1057530.fastq.gz	Fastqsanger.gz
	SRR1057523.fastq.gz	Fastqsanger.gz
	SRR1057524.fastq.gz	Fastqsanger.gz
	SRR1057525.fastq.gz	Fastqsanger.gz
	SRR1057526.fastq.gz	Fastqsanger.gz

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Project description:Gene expression changes associated with prognosis of Merkel cell carcinoma

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Comparative Transcriptional Profiling of human Merkel cells and Merkel Cell Carcinoma

Project description:Merkel cell carcinoma is supposed to be derived from Merkel cells after infection by Merkel cell polyomavirus (MCV) and other poorly known events. A transcriptional profiling with cDNA microarrays was performed on cells from MCV+ Merkel cell carcinomas and isolated normal Merkel cells. This microarray revealed numerous significantly upregulated genes and down-regulated genes. The extensive list of genes identified in these experiments provides a large body of potentially valuable information of Merkel cell carcinoma carcinogenesis and could represent a source of potential targets for cancer therapy. Two-conditions experiment, MCV vs Normal Merkel Cell. Biological replicates : 4 MCV (Cy5), 1 control = pool of Normal Merkel cells from 3 liftings

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Homo sapiens whole blood.

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