Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mus musculus

ABSTRACT: Genome wide transcriptome analysis of skin harboring tissue-resident memory CD8+ T cells

PROVIDER: PRJNA258635 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR1555250.fastq.gz	Fastqsanger.gz
	SRR1555260.fastq.gz	Fastqsanger.gz
	SRR1555270.fastq.gz	Fastqsanger.gz
	SRR1555280.fastq.gz	Fastqsanger.gz
	SRR1555290.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 45

Similar Datasets

Mus musculus

Project description:Tumor antigen specific CD8 Tissue Resident Memory (Trm) Cells

| PRJNA644867 | ENA

Mus musculus

Project description:Development pathway for skin resident memory CD103+CD8+ T cells

| PRJNA203362 | ENA

Genome wide transcriptome analysis of skin harboring tissue-resident memory CD8+ T cells

Project description:Comparison of the transcriptional profiles of full-thickness murine skin harboring tissue resident memory T cells exposed to specific or control trigger Expression profiling by high throughput sequencing

2014-09-11 | E-GEOD-60599 | biostudies-arrayexpress

Mus musculus strain:b6

Project description:Tumor antigen specific CD8 Tissue Resident Memory (Trm) Cells

| PRJNA644934 | ENA

RNA-seq transcriptome analysis of epidermal CD8+CD103+CD49a+ and CD8+CD103+CD49- T cells from healthy human skin

Project description:We report the transcriptome analysis of epidermal CD8 tissue resident memory T (TRM) cells from healthy human skin. Specifically, epidermal CD8+CD103+CD49a+ and CD8+CD103+CD49- TRM cells from healthy human skin were sorted by FACS. Differential gene expression analysis revealed functional dichotomy of epidermal CD8+CD103+CD49a+ and CD8+CD103+CD49- TRM cells.

2017-02-14 | GSE83637 | GEO

Genome wide transcriptome analysis of skin harboring tissue-resident memory CD8+ T cells

Project description:Comparison of the transcriptional profiles of full-thickness murine skin harboring tissue resident memory T cells exposed to specific or control trigger

2014-09-11 | GSE60599 | GEO

Development pathway for skin resident memory CD103+CD8+ T cells

Project description:Tissue resident memory T cells (TRM) provide superior protection against infection localised to extra-lymphoid compartments in the body. Here we show that CD103+CD8+ TRM cells develop in skin from killer cell lectin-like receptor (KLR)G1-negative precursors that selectively infiltrate the epithelial layer. In the skin, a combination of chemokine-guided epithelial entry, local interleukin (IL)-15 and transforming growth factor (TGF)-Î² signalling is required for formation and survival of these long-lived memory cells. Importantly, TRM differentiation results in the gradual acquisition of a unique transcriptional profile that differs from that expressed by memory cells in the circulation and other types of skin-resident intra-epithelial T cells, such as the dendritic epidermal T cells (DETC). We provide a comprehensive molecular and developmental framework for the local differentiation of a distinct type of peripheral memory T cell that contributes to an important first-line of immune defence in barrier tissues such as skin and mucosa. 24 samples were analyzed: 3 replicates of memory gB-T CD8+. CD103+ T cells isolated from the skin of C57/BL6 mice on day 30 p.i. with HSV KOS. 3 replicates of memory P14 CD8+ T cells isolated from gut of mice on day 60 p.i. with LCMV Armstrong. 3 replicates of memory gB-T CD8+ T cells from the lung of mice on day 30 p.i. with influenza WSN. 3 replicates of memory CD62L high CD8+ T cells from the spleen of mice on day 30 p.i. with HSV KOS. 3 replicates of memory CD62L low CD8+ T cells from the spleen of mice of day 30 p.i. with HSV KOS. 3 replicates of Î³Î´-DETC isolated from the skin of C57/BL6 mice on day 30 p.i. with HSV KOS. 3 replicates of Î±Î²-DETC from naive TCRÎ´-/- mice; and 3 replicates of naive gB-T CD8+ T cells from the spleen of naive gB-T transgenic mice.

2013-10-01 | E-GEOD-47045 | biostudies-arrayexpress

Mus musculus

Project description:Molecular signature of brain resident memory CD8+ T cells

| PRJNA170107 | ENA

Project description:Tissue resident memory CD8 T cells

| PRJNA804944 | ENA

CD8 Tissue Resident Memory (TRM) induction

Project description:CD8 Tissue Resident Memory (TRM) induction

| PRJNA1036221 | ENA