Mustela putorius furo
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA259289 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:A restricted period for formation of Outer Subventricular Zone defined by Cdh1 and Trnp1 levels
| PRJNA266982 | ENA
Project description:The domestic ferret (Mustela putorius furo) provides a critical animal model to study human respiratory diseases. However immunological insights are restricted due to a lack of ferret-specific reagents and limited genetic information about ferret B and T cell receptors. Here, variable, diversity and joining genes within the ferret kappa, lambda and heavy chain immunoglobulin loci were annotated using available genomic information. A multiplex PCR approach was derived that facilitated the recovery of paired heavy and light chain immunoglobulin sequences from single sorted ferret B cells, allowing validation of predicted germline gene sequences and the identification of putative novel germlines. Eukaryotic expression vectors were developed that enabled the generation of recombinant ferret monoclonal antibodies. This work advances the ferret as an informative immunological model for viral diseases by allowing the in-depth interrogation of antibody-based immunity.
| S-EPMC7259655 | biostudies-literature
Project description:We investigated sleep ontogenesis in the ferret-a placental mammal that is highly altricial compared to other mammalian species. Because altriciality is linked with elevated rapid-eye-movement (REM) sleep amounts during infancy, it was expected that ferret kits would display very high levels of this state. Longitudinal polysomnographic measurements were made from 8 ferret kits from approximately eye-opening (postnatal day [P]30)-P50 using an experimental routine that minimized the effects of maternal separation. These data were compared to values from 8 adult ferrets (>3 months of age) and 6 neonatal cats (mean age: P31.7). We find that the polygraphic features of REM and non-REM (NREM) sleep are present by at least P30. Over the next 2 weeks, REM sleep amounts slightly declined while wakefulness and NREM sleep amounts increased. However, a comparison to published values from developing cats and rats showed that the ferret did not exhibit a disproportionate amount of REM sleep at similar postnatal ages or relative to a common developmental milestone (eye-opening).
| S-EPMC2527623 | biostudies-literature
Project description:IF001 - Microarray analysis from ferret infections with highly pathogenic reconstructed H1N1 1918 influenza virus.
| PRJNA212790 | ENA
Project description:Ferret single cell transcriptomics analysis
| PRJDB13528 | ENA
Project description:Cdk5 sequencing, CRISPR/Cas9-mediated knockout of the Cdk5 gene in the ferret cerebral cortex.
| PRJDB6112 | ENA
Project description:The cold exposure produce a different gene expression pattern in inguinal and periaortic white adipose
| PRJNA263900 | ENA
Project description:Host Gene Expression Signatures Discriminate between Ferrets Infected with Genetically Similar H1N1 Strains.
| PRJNA140419 | ENA
Project description:Host responses that correlate with respiratory droplet transmission of swine-origin influenza viruses in ferrets.
| PRJNA315396 | ENA