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Caenorhabditis elegans

ABSTRACT: Functional characterization of C. elegans Y-box binding proteins reveals tissue-specific functions and a critical role in the formation of polysomes (RNA-Seq)

PROVIDER: PRJNA265852 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR1635376.fastq.gz	Fastqsanger.gz
	SRR1635377.fastq.gz	Fastqsanger.gz
	SRR1635378.fastq.gz	Fastqsanger.gz
	SRR1635379.fastq.gz	Fastqsanger.gz

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Project description:We present a basic characterization of the function of Y-box binding proteins in C. elegans. Besides playing an important role for fertility in the germline (all four CEY proteins), we found that the presence of CEY-1 and CEY-4 is essential for the assembly of larger polysomes in the soma. We therefore performed ribosome-profiling in combination with total RNA sequencing in wild type and cey-1,-4 double mutant animals to globally compare mRNA levels and their translation status.

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