Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Drosophila melanogaster

ABSTRACT: AGO1 immunoprecipitated small RNAs from D. melanogaster wildtype and mutant ovaries

PROVIDER: PRJNA268781 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR1664731.fastq.gz	Fastqsanger.gz
	SRR1664732.fastq.gz	Fastqsanger.gz
	SRR1664734.fastq.gz	Fastqsanger.gz
	SRR1664736.fastq.gz	Fastqsanger.gz

Items per page:

1 - 4 of 4

Similar Datasets

Drosophila melanogaster

Project description:Drosophila melanogaster small RNAs in ovaries

| PRJNA215819 | ENA

Drosophila melanogaster

Project description:Small RNAs from Drosophila melanogaster WT and Tailor mutant S2 cells and ovaries

| PRJNA281580 | ENA

Drosophila melanogaster

Project description:Expression analysis of wildtype (OregonG) and upSET mutant ovaries.

| PRJNA156227 | ENA

Cut&Run in Drosophila melanogaster control, mutant and knockdown ovaries

Project description:H3K27me3 profiles using Cleavage under targets and Release using nuclease (Cut&Run) in control and KD Drosophila melanogaster ovaries. We examined the impact on chromatin profiles in Drosophila melanogaster ovaries in which the lid, the Sin3a, the Snr1 or the mod(mdg4) gene have been selectively knocked down by tissue-specific shRNA expression. We additionally explored H3K27me3 and H3K9me3 in control and dhd mutant ovaries either carrying or not a transgene.

2021-12-10 | GSE174250 | GEO

Drosophila melanogaster

Project description:Small RNAs from third instar Drosophila melanogaster males

| PRJNA262549 | ENA

Drosophila melanogaster

Project description:Drosophila melanogaster ovaries R-loops

| PRJNA1112819 | ENA

Drosophila melanogaster

Project description:Drosophila melanogaster DNA genomic sequencing and small RNAs sequencing

| PRJNA104947 | ENA

Drosophila melanogaster

Project description:piRNA libraries from Drosophila melanogaster ovaries

| PRJNA98965 | ENA

Pleiotropic Fitness Effects of the lncRNA Uhg4 in Drosophila melanogaster

Project description:Long noncoding RNAs (lncRNAs) are a diverse class of RNAs that are critical for gene regulation, DNA repair and splicing, and have been implicated in cancer, stress response, and development. However, the function of many lncRNAs remains unknown. In Drosophila melanogaster, U snoRNA host gene 4 (Uhg4) encodes an antisense long noncoding RNA that is host to seven small nucleolar RNAs (snoRNAs). Uhg4 is expressed ubiquitously during development and in all adult fly tissues with maximal expression in ovaries; however, it has no annotated function(s). Here, we used CRISPR-Cas9 germline gene editing to generate multiple deletions spanning the promoter region and first exon of Uhg4. Mutant flies were sterile, showed delayed development and decreased viability, and changes in sleep and responses to stress. Whole genome RNA sequencing of Uhg4 deletion flies and their controls identified coregulated genes and genetic interaction networks. Gene ontology analyses highlighted a broad spectrum of biological processes, including morphogenesis, stress response, and regulation of transcription and translation. Thus, Uhg4 is a lncRNA essential for reproduction with pleiotropic effects on multiple fitness traits.

2022-04-26 | GSE199865 | GEO

Drosophila melanogaster

Project description:The small RNA profile in wildtype, R2D2 and loquacious mutant Drosophila

| PRJNA121125 | ENA