Spraguea lophii
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA269798 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Spraguea lophii 42_110 Genome sequencing and assembly
| PRJNA73605 | ENA
Project description:Lipomyces genome scale model based on the Lipomyces starkeyi NRRL-11557 genome.
Published in:
Genome-Scale Model Development and Genomic Sequencing of the Oleaginous Clade Lipomyces
Frontiers in Bioengineering and Biotechnology
Industrial Biotechnology
Volume 12 - 2024 | doi: 10.3389/fbioe.2024.1356551
2024-03-20 | MODEL2403190001 | BioModels
Project description:Spraguea lophii Transcriptome or Gene expression
| PRJNA209348 | ENA
Project description:Recent advances in nucleic acid sequencing now permit rapid and genome-scale analysis of genetic variation and transcription, enabling population-scale studies of human biology, disease, and diverse organisms. Likewise, advances in mass spectrometry proteomics now permit highly sensitive and accurate studies of protein expression at the proteome-scale. However, most proteomic studies remain limited to the analysis of canonical reference proteomes. Here, we develop ProteomeGenerator2 (PG2), based on the scalable and modular ProteomeGenerator framework. PG2 integrates genome and transcriptome sequencing to incorporate protein variants containing amino acid substitutions, insertions, and deletions, as well as non-canonical reading frames, exons, and other variants caused by genomic and transcriptomic variation. PG2 can be integrated with current and emerging sequencing technologies, assemblers, variant callers, and mass spectral analysis algorithms, and is available open-source from https://github.com/kentsisresearchgroup/ProteomeGenerator2.
2024-05-22 | PXD037061 | Pride
Project description:The CHARM (Cancer Health Assessment Reaching Many) study will assess the utility of clinical exome sequencing and how it affects care in diverse populations. The study population includes adults at risk for hereditary cancer syndromes.
The primary objective is to implement a hereditary cancer risk assessment program in healthy 18-49 year-olds in primary care settings within a vertically integrated health delivery system (Kaiser Permanente) and a federal qualified health center (Denver Health). The investigators will assess clinical exome sequencing implementation and interpretation, as well as tailored interactions for low health literacy including a contextualized consent process, and a modified approach to results disclosure and genetic counseling. The investigators will also assess the clinical utility (healthcare utilization and adherence to recommended care) and personal utility of primary and additional results from clinical exome sequencing, and evaluate the ethical and policy implications of considering personal utility of genomic information decisions for health care coverage.
| 2265388 | ecrin-mdr-crc
Project description:Null mutations for genes encoding the major seed storage protein in pea, vicilin, were sought among a fast-neutron mutant population. Combinations of four and five mutations, where individual vicilin loci had been deleted, were generated to address the question of how removal or reduction of a major storage protein would impact on seed protein concentration and yield. While seed protein concentrations were not reduced in mutant lines, indicative of a re-balancing of the proteome, there were notable differences in their metabolite, proteomic and amino acid profiles. The genomic regions which were deleted were defined by whole genome sequencing of the parental line, JI2822 and its quintuple vicilin null derivative.
2025-01-27 | PXD048561 | Pride
Project description:Null mutations for genes encoding the major seed storage protein in pea, vicilin, were sought among a fast-neutron mutant population. Combinations of four and five mutations, where individual vicilin loci had been deleted, were generated to address the question of how removal or reduction of a major storage protein would impact on seed protein concentration and yield. While seed protein concentrations were not reduced in mutant lines, indicative of a re-balancing of the proteome, there were notable differences in their metabolite, proteomic and amino acid profiles. The genomic regions which were deleted were defined by whole genome sequencing of the parental line, JI2822 and its quintuple vicilin null derivative.
2025-01-27 | PXD048566 | Pride