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Homo sapiens

ABSTRACT: Effect in MOLM-14 cells of 24hr cortistatin A treatment on gene expression

OTHER RELATED OMICS DATASETS IN: GSE65161

PROVIDER: PRJNA273292 | ENA |

REPOSITORIES: ENA

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Homo sapiens

Project description:Effect in MOLM-14 cells of 3hr cortistatin A treatment on gene expression

| PRJNA273291 | ENA

Effect in MOLM-14 cells of 24hr cortistatin A treatment on gene expression

Project description:We characterized the marine natural product cortistatin A (CA) as an inhibitor of CDK8 to determine whether pharmacologic inhibition of CDK8 regulates super-enhancer function and inhibits AML proliferation. In this series, we examine the transcriptional effect on MOLM-14 cells of 24hrs exposure to CA.

2015-09-25 | GSE65014 | GEO

Effect in MOLM-14 cells of 3hr cortistatin A treatment on gene expression

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Project description:Effect in HCT116 cells of 3hr cortistatin A treatment on gene expression.

| PRJNA273294 | ENA

Homo sapiens

Project description:Effect in K562 cells of 3hr cortistatin A treatment on gene expression

| PRJNA273293 | ENA

Homo sapiens

Project description:Effect of 4hr cortistatin A treatment on gene expression in SET2 cells.

| PRJNA273296 | ENA

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Project description:Effect in MV4 11 cells of 3hr cortistatin A treatment on gene expression

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Homo sapiens

Project description:DMSO control and DZNep treated MOLM-14 cells

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Homo sapiens Transcriptome or Gene expression

Project description:Asthma is a chronic inflammatory airway disease characterized by airway inflammation and remodeling. The role of 15-oxo-5Z,8Z,11Z,13E-eicosatetraenoic acid (15-oxoETE), a 15-HETE metabolite catalyzed by 15-prostaglandin dehydrogenase (15-PGDH), has been relatively unexplored in asthma. In this study, we used RNA-seq to explore the effect of 15-KETE on the transcriptome of airway epithelial cells, aiming to identify its potential downstream targets and mechanisms of action.

2026-05-21 | GSE325003 | GEO

Homo sapiens

Project description:24hr CA treatment vs. DMSO in HCT116 cells (from 'Identification of CDK8 and CDK19 substrates in human cells using cortistatin A and quantitative phosphoproteomics')

| PRJNA313158 | ENA

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