Project description:Parasite gene expression differences have been reported previously between RH-ERP, RH-JSR and GT1. To independently confirm these gene expression differences, we examined the parasite gene expression profiles of RH-ERP, RH-JSR and GT1 through microarray. Three type I strains of Toxoplasma gondii were compared with one array each, and these were used to verify data from previous studies.
Project description:This experiment sough to understand the impact Toxoplasma gondii infection on the host transcriptome. We do this by sequencing both Total and Small RNA from 6 donors. Infection results is singificant alterations to both gene expression and miRNA experession. The GT1 strain of T. gondii induces different changes to that of GHPT strain.