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Toxoplasma gondii ME49

ABSTRACT: Toxoplasma gondii ME49

PROVIDER: PRJNA28893 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	SRR173013.fastq.gz	Fastqsanger.gz
	SRR173023.fastq.gz	Fastqsanger.gz
	SRR173027.fastq.gz	Fastqsanger.gz
	SRR173028.fastq.gz	Fastqsanger.gz

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Toxoplasma gondii ME49

Project description:Toxoplasma gondii ME49 Raw sequence reads

| PRJNA436351 | ENA

RNA-seq data analysis of TgSNF2L on Toxoplasma gondii development [ME49 SNF2L RNAseq]

Project description:To investigate transcriptional role of TgSNF2L on type II Toxoplasma gondii (ME49 Tir1), an auxin inducible degron system was introduced to control the protein expression of TgSNF2L after adding IAA.

2025-05-23 | GSE268892 | GEO

Strain-dependent host responses in chicken embryonic fibroblasts infected with Toxoplasma gondii [ME49, CEP, and Mock]

Project description:Toxoplasma gondii is a ubiquitous protozoan pathogen able to infect both mammalian and avian hosts. Surprisingly, just three strains appear to account for the majority of isolates from Europe and N. America. To test the hypothesis that strain divergence might be driven by differences between mammalian and avian response to infection, we examine in vitro strain-dependent host responses in a representative avian host, the chicken. Chicken embryonic fibroblasts were cultivated in vitro and infected with different strains of Toxoplasma gondii (Type II = ME49, Type III = CEP); host transcriptional responses were then analyzed at 24 hours post-infection.

2011-05-27 | E-GEOD-29562 | biostudies-arrayexpress

RNA-seq data analysis of TgAP2XII-1 on Toxoplasma gondii merozoites development [ME49 XII-1 RNAseq]

Project description:To investigate transcriptional role of TgAP2XII-1 on type II Toxoplasma gondii (ME49 Tir1), an auxin inducible degron system was introduced to control the protein expression of TgAP2XII-1 and the target protein could be totally degradated in 3h after adding IAA.

2023-05-01 | GSE228580 | GEO

HFF Cells: Control vs. Toxoplasma gondii infected

Project description:Expression profile microarray of human foreskin fibroblast cell comparing control untreated HFF cell with HFF cell infected with ME49 strain.Study on Toxoplasma gondii infection of HFF cell LncRNAs expression, for further studies on the differential exprssion of LncRNAs in HFF cell against the infection of Toxoplasma gondii research provide the basic function.

2017-01-01 | GSE92603 | GEO

A novel nuclear protein complex controlling the expression of developmentally regulated genes in Toxoplasma gondii [RNA-seq]

Project description:To investigate the transcriptional effects of TgAP2XII-5 on type II Toxoplasma gondii (ME49) in the tachyzoite and bradyzoite stages. Also, to study the transcriptional role of TgAIP1 on ME49 tachyzoites.

2024-12-19 | GSE277550 | GEO

RNA-seq data analysis of TGME49_203980 on Toxoplasma gondii development [TGME49_203980 RNAseq]

Project description:To investigate transcriptional role of TGME49_203980 on type II Toxoplasma gondii (ME49 Tir1), an auxin inducible degron system was introduced to control the protein expression of TGME49_203980 after adding IAA.

2025-05-23 | GSE268652 | GEO

RNA-seq data analysis of TGME49_217480 on Toxoplasma gondii development [TGME49_217480 RNAseq]

Project description:To investigate transcriptional role of TGME49_217480 on type II Toxoplasma gondii (ME49 Tir1), an auxin inducible degron system was introduced to control the protein expression of TGME49_217480 after adding IAA.

2025-05-23 | GSE268750 | GEO

mRNA-seq of immortailized bone marrow derived macrophages (iBMDM) infected with type II Toxoplasma gondii

Project description:Analysis of mRNA-seq reveals difference in gene expression profiles of wild type iBMDM, IRF3-/- iBMDM and IRF7-/- iBMDM infected with ME49, a type II Toxoplasma gondii

2019-03-25 | GSE128752 | GEO

RESTRICTION checkpoint controls bradyzoite development in Toxoplasma gondii

Project description:The Toxoplasma gondii G1 RESTRICTION checkpoint operates the switch between parasite growth and differentiation. The Cdk-related G1 kinase TgCrk2 forms alternative complexes with atypical cyclins (TgCycP1, TgCycP2 and TgCyc5) in the rapidly dividing developmentally incompetent RH and slower dividing developmentally competent ME49 tachyzoites and bradyzoites. The TgCycP1 expression interferes with bradyzoite differentiation. The TgCycP2 regulates G1 in the developmentally competent ME49 but not in the developmentally incompetent RH tachyzoites. Examination of TgCycP2 and TgCyc5 in alkaline induced and spontaneous bradyzoite differentiation (rat embryonic brain cells) models confirmed TgCycP2 role in bradyzoite replication and revealed that stress induced TgCyc5 is critical for efficient tissue cyst maturation.

2022-04-23 | GSE200962 | GEO

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