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Homo sapiens

ABSTRACT: Epigenetic profiling of Juvenile Idiopathic Arthritits (JIA) patients

OTHER RELATED OMICS DATASETS IN: E-GEOD-71595

PROVIDER: PRJNA291598 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR2138100.fastq.gz	Fastqsanger.gz
	SRR2138110.fastq.gz	Fastqsanger.gz
	SRR2138120.fastq.gz	Fastqsanger.gz
	SRR2138130.fastq.gz	Fastqsanger.gz
	SRR2138140.fastq.gz	Fastqsanger.gz

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Project description:Gene expression on peripheral blood mononuclear cells (PBMC) from SPARKS CHARMS juvenile idiopathic arthritis (JIA) cohort pre and post methotrexate therapy. This is the first study to our knowledge, to evaluate gene expression profiles in children with JIA before and after MTX, and to analyze genetic variation in differentially expressed genes. We have identified a gene, which may contribute to genetic variability in MTX response in JIA. PBMC were isolated from blood samples taken from 11 patients with JIA pre methotrexate therapy and at 6 months into therapy

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Project description:CD4+ T Cells Gene Expression-Based Biomarkers in Juvenile Idiopathic Arthritis (JIA)

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