Project description:Effects of TRPC1 silencing on whole-transcriptome gene expression were determined in human primary aortic vascular smooth muscle cells using whole-transcriptome gene expression profiling.
Project description:Transcriptional Profiling of Human Airway Smooth muscle cells from subjects with and without asthma-effects of mimicking viral challenge
Project description:Smooth muscle cell TGFβ signaling is one of the primary drivers of smooth muscle cell maturation. Inhibition of smooth muscle cell TGFβ signaling in hyperlipidemic mice induces vessel wall inflammation and vessel wall dilation/dissection and leads aortic aneurysm. We performed bulk RNAseq method to examine smooth muscle cell gene expression profile using fresh human tissues from normal aortic media smooth muscle cells and aneurysm aortic media smooth muscle cells.
Project description:Analysis of gene expression in primary cultured human aortic endothelial cells (HAECs) and primary cultured human aortic smooth muscle cells (SMCs) with or without H2O2 or Collagen tripeptide (CTP)
Project description:Human primary aortic smooth muscle cells were infected with wild type (W50, 381), W50 derived gingipain mutants (E8 and K1A), or 381 derived fimbriae mutants (DPG3 and KRX178) strains of Porphyromonas gingivalis for 24 hours. The RNA was extracted from the cells and human whole genome microarray were used to measure gene expression.
