Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Malassezia

ABSTRACT: Malassezia furfur and Malassezia Pachydermatis genome sequencing and assembly

OTHER RELATED OMICS DATASETS IN: PXD004523

PROVIDER: PRJNA322049 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR3540803_1.fastq.gz	Fastqsanger.gz
	SRR3540803_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 3 of 3

Similar Datasets

Metabolic reconstruction of lipid metabolism of Malassezia

Project description:Malassezia species are lipophilic and lipid dependent yeasts belonging to the human and animal microbiota. Typically, they are isolated from regions rich in sebaceous glands. They have been associated with dermatological diseases such as seborrheic dermatitis, tinea versicolor, atopic dermatitis, and folliculitis. Genome sequences of Malassezia globosa, Malassezia sympodialis, and Malassezia pachydermatis lack genes related to fatty acid synthesis. Here, lipid synthesis pathways of M. furfur, M. pachydermatis, M. globosa, M. sympodialis and an atypical variant of M. furfur were reconstructed using genome data and Constraints Based Reconstruction and Analysis. The metabolic reconstruction allowed us to predict variation in the fluxes of each reaction over the network to satisfy the biomass objective function. Proteomic profiling improved and validated the models through data integration. Results suggest that several mechanisms including steroid and butanoate metabolism explain the yeast’s growth under different lipid conditions. Flux differences were observed in production of riboflavin in M. furfur and the biosynthesis of glycerolipids in the atypical variant of M. furfur and Malassezia sympodialis.

2017-10-02 | PXD004523 | Pride

Malassezia

Project description:Malassezia furfur and Malassezia Pachydermatis genome sequencing and assembly

| PRJNA288787 | ENA

Characterization of the genes that were regulated by infection with Malassezia furfur

Project description:In the present study, we investigated the pathogenicity of infection with Malassezia furfur using Caenorhabditis elegans as a model animal. The lifespan of the adult C. elegans infeted with Malassezia furfur was significantly longer than that of uninfected animals (control). Transcriptional profiling comparing infected- and uninfected animals suggested that genes related to the innate immunity were upregulated by infection with Malassezia furfur.

2025-03-06 | GSE260976 | GEO

The genomic tandem quadruplication is associated with ketoconazole resistance of Malassezia pachydermatis

Project description:Purpose: Understanding the ketoconazole resistance mechanism in Malassezia pachydermatis Methods: The transcriptome profile of the ketoconazole resistant M. pachydermatis KCTC 27587 cells compared to that of ketoconazole sensitive M. pachydermatis CBS 1879 cells were generated by RNA-Seq using Illumina HiSeq. Results: The expressions of genes in the region of quadruplicated chromosome 4 were up-regulated.

2019-02-07 | GSE118354 | GEO

Malassezia pachydermatis

Project description:Malassezia pachydermatis Genome sequencing and assembly

| PRJNA639054 | ENA

Malassezia furfur

Project description:Malassezia furfur Genome sequencing and assembly

| PRJNA732434 | ENA

Malassezia furfur

Project description:Malassezia furfur Genome sequencing and assembly (CBS7982)

| PRJNA779728 | ENA

Malassezia furfur

Project description:Malassezia furfur overview