Project description:Comparative proteomic analysis of Fusobacterium nucleatum clinical strains isolated from brain abscess patients and the standard strain ATCC 25586, using label-free quantification (LFQ) to identify differentially expressed proteins and explore pathogenic mechanisms related to brain abscess.
2026-03-23 | PXD076046 |
Project description:Microbiota in adult perianal abscess revealed by metagenomic next-generation sequencing
Project description:Here, we used a saturated transposon insertion mutant pool of P. aeruginosa strain PAO1 and transposon insertion sequencing (Tn-Seq), to identify genes conditionally important for survival under conditions mimicking the environment of a nosocomial infection. Conditions tested included tissue culture medium with and without human serum, a murine abscess model, and a human skin organoid model.
