Coronaviridae
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA32225 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Coronavirus Genome Sequencing Project for J. Craig Venter Institute
| PRJNA260063 | ENA
Project description:This chapter describes the properties of coronaviruses and features of the diseases they cause in animals.
| S-EPMC7149743 | biostudies-literature
Project description:Publisher Summary This chapter focuses on Coronaviridae family whose two subfamilies include Coronavirinae and Torovirinae. The member genera include Alphacoronavirus, Betacoronavirus, Gammacoronavirus, Torovirus, and Bafinivirus. The members of the family Coronaviridae are enveloped and positive stranded RNA viruses of three classes of vertebrates, which include corona- and toroviruses for mammals, coronaviruses for birds, and bafiniviruses for fishes. The nucleocapsids are helical and can be released from the virion by treatment with detergents. Where the coronavirus nucleocapsid appears to be loosely wound, those of the Torovirinae are distinctively tubular. The entire replication cycle takes place in the cytoplasm and involves the production of full-length and subgenome-sized (sg) minus-strand RNA intermediates with the viral genome serving both as mRNA for the replicase polyproteins and as a template for minus-strand synthesis. Members of the family Coronaviridae all seem to share two envelope protein species, the membrane (M) and spike (S) proteins. Similarities in size, predicted structures and presumed function(s) suggest a common ancestry, and the remote, but significant sequence similarities observed for toro-, bafini-, and (to lesser extent) coronavirus S proteins lend further support to this view. The replicase polyproteins of the Coronaviridae comprise a number of characteristic domains arranged in a conserved order.
| S-EPMC7149967 | biostudies-literature
Project description:Streptococcus pyogenes (Group A Streptococcus: GAS) is a major human pathogen that causes streptococcal pharyngitis, skin and soft-tissue infections, and life-threatening conditions such as streptococcal toxic shock syndrome (STSS). A large number of virulence-related genes are encoded on GAS genomes, which are involved in host-pathogen interaction, colonization, immune invasion, and long-term survival within hosts, causing the diverse symptoms. Here, we investigated the interaction between GAS-derived extracellular vesicles and host cells in order to reveal pathogenicity mechanisms induced by GAS infection.
2021-05-17 | PXD026040 | JPOST Repository
Project description:To allow the characterization of the populations of small RNAs in the testes of mutant animal, small-RNA fraction of total testis RNA was isolated and sequenced.
2016-11-18 | GSE89995 | GEO