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Mus musculus

ABSTRACT: RNAseq changes in fibroblasts after treatment with selected protein(s) or E16.5 skin extract

PROVIDER: PRJNA337890 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR4004735_1.fastq.gz	Fastqsanger.gz
	SRR4004735_2.fastq.gz	Fastqsanger.gz
	SRR4010250_1.fastq.gz	Fastqsanger.gz
	SRR4010250_2.fastq.gz	Fastqsanger.gz
	SRR4010251_1.fastq.gz	Fastqsanger.gz

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RNAseq changes in fibroblasts after treatment with selected protein(s) or E16.5 skin extract

Project description:Purpose: To identify the cellular processes upregulated in fibroblasts after treatment with selected protein(s) or E16.5 skin extract Methods: To explore the mechanism of extract-induced HF neogenesis, adult dermal fibroblasts were cultured in the presence of E16.5 extract or selected protein(s) for 3 days before being tested. Results: we determined how the exposure of adult fibroblasts to E16.5 extract, the selected protein mix or each of the selected proteins and compared the resultant transcriptomes with those of adult DP and embryonic dermal fibroblasts. Conclusions: Gene expression of adult fibroblasts exposed to E16.5 extract and selected proteins mix, the key DP signature genes became upregulated.

2016-08-10 | GSE85303 | GEO

RNAseq changes in fibroblasts after treatment with selected protein(s) or E16.5 skin extract

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Project description:RNAseq changes in human fibroblasts after treatment with E16.5 skin extract

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RNAseq changes in human fibroblasts after treatment with E16.5 skin extract

Project description:To identify the cellular processes upregulated in fibroblasts after treatment with E16.5 skin extract

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RNAseq of quiescent (Q) and stress induced premature senescent (SIPS) fibroblasts treated with plant extract (1201) from Solidago vigaurea subspecies alpestris

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Serpinb3a contributes to early skin inflammation following allergen exposure

Project description:Serpinb3a knockout mice show attenuated Transepidermal Water Loss (TEWL) and S100A8 expression (an early inflammatory marker) following treatment with Aspergillus fumigatus extract. The aim of the RNAseq experiments was to provided mechanistic insight for the role of Serpinb3a by identifying early differences in gene expression following allergen exposure. Wild type Balb/c and Serpinb3a null mouse backs were shaved and 24 hours later a patch containing 200ug of Aspergillus fumigatus extract was applied to the skin. After 3 days the patch was removed and the skin was harvested after an additional 24 hours.

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Evaluation of the Effects of Sumac (Rhus coriaria) Extract-Loaded Ethosomes on a Wound Healing in vitro Model

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