Project description:We konckout PARK2 in Esophageal Squamous Cell Cancer Cell Line EC9706 and then detected differentially expressed genes We konckout PARK2 in Esophageal Squamous Cell Cancer Cell Line EC9706 and then detected differentially expressed genes
Project description:This study was designed to identify genes aberrantly expressed in esophageal squamous cell carcinoma (ESCC) cells. Three esophageal squamous cell carcinoma-derived cell lines and one normal human esophageal squamous cell line were analyzed.
Project description:Transcriptional profiling of Human Esophageal Squamous Cell Cancer Cell line (KYSE520) comparing mock transfectant (KYSE520 Mock②) with cells transfected with a mir203 expression vector (KYSE520 miR203⑥)
Project description:Paclitaxel is commonly used as a second-line treatment for gastric cancer, but the mechanisms underlying paclitaxel resistance remain to be further investigated. To address this, we successfully established a mouse gastric adenocarcinoma cell line (MPC) from murine gastric adenocarcinoma organoids. Subsequently, a paclitaxel-resistant cell line (MPC-PTX) was generated through multi-cycle drug stimulation. This model provides a valuable tool for studying the mechanisms of paclitaxel resistance in gastric cancer.
Project description:Transcriptional profiling of Human Esophageal Squamous Cell Cancer Cell line (KYSE520) comparing mock transfectant (KYSE520 Mock②) with cells transfected with a mir203 expression vector (KYSE520 miR203⑥) KYSE520 Mock② VS KYSE520 miR203⑥
Project description:We analyzed ChIP-seq, chromatin accessibility and RNA-seq across mouse esophageal squamous organoids and human esophageal squamous cell cancer
Project description:We analyzed ChIP-seq, chromatin accessibility and RNA-seq across mouse esophageal squamous organoids and human esophageal squamous cell cancer