Project description:Celiac disease is a chronic immune-mediated disorder with an important genetic component. We analyzed the expression of candidate genes and regulatory elements in biopsies from duodenum.
Project description:Celiac disease is a chronic immune-mediated disorder with an important genetic component. We analyzed the expression of candidate new genes and regulatory elements (2) in biopsies from duodenum.
Project description:Celiac disease is a chronic immune-mediated disorder with an important genetic component. We analyzed the expression of candidate new genes (2) and regulatory elements (3) in biopsies from duodenum.
Project description:Asthma is a chronic inflammatory airway disease characterized by airway inflammation and remodeling. The role of 15-oxo-5Z,8Z,11Z,13E-eicosatetraenoic acid (15-oxoETE), a 15-HETE metabolite catalyzed by 15-prostaglandin dehydrogenase (15-PGDH), has been relatively unexplored in asthma. In this study, we used RNA-seq to explore the effect of 15-KETE on the transcriptome of airway epithelial cells, aiming to identify its potential downstream targets and mechanisms of action.
Project description:Celiac disease is a chronic immune-mediated disorder with an important genetic component. We analyzed the expression of regulatory elements (4) and some of their targets in biopsies from duodenum.
