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Mus musculus

ABSTRACT: Genome-wide maps of chromatin state in neural stem/progenitor cells (NSC) from mouse neonatal forebrain [ChIP-seq]

PROVIDER: PRJNA355014 | ENA |

REPOSITORIES: ENA

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Dataset's files

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			Action	DRS
	SRR5058100.fastq.gz	Fastqsanger.gz
	SRR5058101.fastq.gz	Fastqsanger.gz
	SRR5058102.fastq.gz	Fastqsanger.gz
	SRR5058095.fastq.gz	Fastqsanger.gz
	SRR5058096.fastq.gz	Fastqsanger.gz

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Project description:Genome-wide maps of chromatin state in neural stem/progenitor cells (NSC) from mouse neonatal forebrain [ChIA-PET]

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Project description:Genome-wide chromatin state maps of murine embryonic stem (ES) cells, ES-derived neural progenitor cells and whole brain tissue. The data were generated to examine the correlation between histone and DNA methylation during lineage-commitment. Keywords: High-throughput ChIP-sequencing, Illumina, cell type comparison H3K4me3, H3K4me2 and/or H3K4me1 ChIP-Seq in singlicate from mouse embryonic stem (ES) cells, ES-derived neural progenitor cells and whole brain tissue suspensions Raw sequence data files for this study are available for download from the SRA FTP site at ftp://ftp.ncbi.nlm.nih.gov/sra/Studies/SRP000/SRP000230

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Project description:We report the application of single-molecule-based sequencing technology for high-throughput profiling of histone modifications in NSC. By obtaining sequences from chromatin immunoprecipitated DNA, we generated genome-wide chromatin-state maps of NSC. We compared histone modifications between wild type and Sox2-deleted NSC.

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