Project description:To investigate the effect of GAGE12I and SPIN4 on the gene expression profile in gastric cancer cells, genome-wide mRNA changes were analyzed by mRNA microarray upon overexpressing GAGE12I and SPIN4 in BGC823 gastric cancer cells.
Project description:In order to explore the effect of miRNA on TRAIL sensitivity of gastric cancer, we selected TRAIL-sensitive MKN45 and TRAIL-resistant BGC823 gastric cancer cell line. The expression of miRNA in MKN45 and BGC823 was detected by miRNA chip. "3" is the miRNA expression file of BGC823. "4" is the miRNA expression file of MKN45.
Project description:Gene expression profiling of immortalized human mesenchymal stem cells with hTERT/E6/E7 transfected MSCs. hTERT may change gene expression in MSCs. Goal was to determine the gene expressions of immortalized MSCs.
Project description:Galangin-containing exosomes (Galangin-Exo) were isolated from BGC823 cells treated with Galangin.RNA-seq technology was used to screen differentially expressed MicroRNAs (miRNAs) in Galangin-Exo. BGC823 cells can specifically take up Galangin-Exo. In addition, Galangin-Exo inhibited the growth of gastric cancer cells.