Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Homo sapiens

ABSTRACT: POLR3G Dependent PolyA+ and smallRNA Transcriptomes in Human Pluripotent Stem Cells

PROVIDER: PRJNA371846 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR5239180_1.fastq.gz	Fastqsanger.gz
	SRR5239180_2.fastq.gz	Fastqsanger.gz
	SRR5239190.fastq.gz	Fastqsanger.gz
	SRR5239181_1.fastq.gz	Fastqsanger.gz
	SRR5239181_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 24

Similar Datasets

E-MTAB-3158

Project description:Transcriptional Profiling of human pluripotent stem cells and and derived tissues

2025-01-23 | E-MTAB-3158 | ExpressionAtlas

E-MTAB-7938

Project description:RNA-Seq of GNRH1 neurons differentiated from human pluripotent stem cells

2025-01-23 | E-MTAB-7938 | ExpressionAtlas

E-GEOD-54112

Project description:ZNF804A transcriptome networks in differentiating human neurons derived from induced pluripotent stem cells

2025-01-24 | E-GEOD-54112 | ExpressionAtlas

E-MTAB-7000

Project description:Epithelium-only cultured stem cells isolated from human pluripotent stem cell derived intestinal organoids grown in matrigel and alginate

2025-01-23 | E-MTAB-7000 | ExpressionAtlas

POLR3G Dependent PolyA+ and smallRNA Transcriptomes in Human Pluripotent Stem Cells

Project description:POLR3G is expressed at high levels in human pluripotent stem cells (hPSCs) and is required for maintenance of stem cell state through mechanisms, which are not known in detail. In order to explore how POLR3G regulates stem cell state, we have carried out deep sequencing analysis of polyA+ and smallRNA transcriptomes present in hPSCs and regulated in POLR3G dependent manner. Our data reveals that POLR3G regulates a specific subset of the hPSC transcriptome, including multiple transcripts types, such as protein coding genes, lincRNAs, miRNAs and snoRNAs. The primary function of POLR3G is in the maintenance rather than repression of transcription. The majority of POLR3G polyA+ transcriptome is regulated during differentiation and the key pluripotency factors bind to the promoters of at least 30 % of the POLR3G regulated transcripts. The POLR3G transcriptome is functionally linked to embryonic development and important tasks in cellular maintenance and function. #!/bin/bash

2017-05-10 | GSE94696 | GEO

Homo sapiens immortalized MSCs: 3A6

Project description:Gene expression profiling of immortalized human mesenchymal stem cells with hTERT/E6/E7 transfected MSCs. hTERT may change gene expression in MSCs. Goal was to determine the gene expressions of immortalized MSCs.

2010-09-25 | GSE24338 | GEO

E-MTAB-5230

Project description:RNA-seq of WTAP knockdown human pluripotent stem cells during the exit from pluripotency induced by Activin/Nodal inhibition

2025-01-23 | E-MTAB-5230 | ExpressionAtlas

E-MTAB-2031

Project description:RNA-Seq of 3iL human embryonic stem cells with an induced expression profile that more closely resembles native pluripotent cells and uninduced controls

2025-01-23 | E-MTAB-2031 | ExpressionAtlas

Homo sapiens MSCs: Normoxia vs. Hypoxia

Project description:Transcriptional profiling of human mesenchymal stem cells comparing normoxic MSCs cells with hypoxic MSCs cells. Hypoxia may inhibit senescence of MSCs during expansion. Goal was to determine the effects of hypoxia on global MSCs gene expression.

2011-02-19 | GSE20463 | GEO

E-MTAB-7979

Project description:RNA-seq of human pluripotent cells with ancient ADSL

2025-01-23 | E-MTAB-7979 | ExpressionAtlas