Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Homo sapiens

ABSTRACT: Genome-wide maps of chromatin state difference in KMT2D Knockdown/Control PC-3 Cells

PROVIDER: PRJNA374514 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR5298734.fastq.gz	Fastqsanger.gz
	SRR5298735.fastq.gz	Fastqsanger.gz

Items per page:

1 - 2 of 2

Similar Datasets

Analysis of KMT2D Knockdown/Control PC-3 Cell Line

Project description:Analysis of KMT2D Knockdown/Control PC-3 Cell Line

| PRJNA374508 | ENA

Genome-wide maps of chromatin state in KMT2D Knockout and KMT2D WT melanoma in mice

Project description:Genome-wide maps of chromatin state in KMT2D Knockout and KMT2D WT melanoma in mice

| PRJNA480444 | ENA

Next Generation Sequencing Facilitates Quantitative Analysis of KMT2D Knockdown/Control PC-3 Cell Line Transcriptomes

Project description:KMT2D is a histone methyltransferase for catalyzing the monomethylation of H3K4. Previous studies have indentified that H3K4me1 is prominent on active enhancers and participates in gene expression regulation. To further examine the transcriptional changes in response to KMT2D depletion, we performed RNA-seq with KMT2D knockdown and control PC-3 cells by BGISEQ-500

2018-10-23 | GSE94807 | GEO

Genome-wide maps of chromatin state difference in KMT2D Knockdown/Control PC-3 Cells

Project description:KMT2D is a histone methyltransferase for catalyzing the monomethylation of H3K4. The H3K4me1 is prominent on active enhancers and participates in gene expression regulation. Loss of KMT2D in cancer has been approved to impact on a set of gene expression by the reduction of H3K4me1 level. To identify the direct target of KMT2D in prostate cancer, we performed H3K4me1 ChIP-seq with KMT2D knockdown and control PC-3 cells.

2018-10-23 | GSE94816 | GEO

Homo sapiens

Project description:Next Generation Sequencing Facilitates Quantitative Analysis of KMT2D Knockdown/Control PC-3 Cell Line Transcriptomes

| PRJNA374489 | ENA

Homo sapiens

Project description:Genome-wide maps of chromatin state in NCCIT cells

| PRJNA135813 | ENA

Homo sapiens

Project description:Genome-wide maps of chromatin state ATRA treated and control HL-60 cells [ChIP-seq]

| PRJNA363022 | ENA

ChIP-seq and RNA-seq analysis of KMT2D-silenced metastatic melanoma cells

Project description:Purpose: Study of the mechanism trough which KTM2D regulates chromatin modification and transcription in a xenograft model of human metatstatic melanoma Methods: We generated patient derived xenografts (PDXs) from metastatic melanoma (MM) biopsies of three different patients. The MMs carry NRASQ61L, NRASQ61Q or BRAFV600 mutations. Cells from secondary PDX (PDX2) were transduced with lentiviral vectors carrying Luciferase (shLuc) and KMT2D (shKMT2D) hairpins and mRNA profiles and genome-wide chromatin-state maps were generated by deep sequencing using Illumina HiSeq2000. Results: we found that KMT2D regulates the activity of a subset of enhancers required for expression of specific genes.

2016-04-21 | GSE71854 | GEO

Homo sapiens

Project description:Genome-wide maps of chromatin state for H3.3 tagged cells

| PRJNA192851 | ENA

Homo sapiens

Project description:Genome-wide maps of chromatin state for HIRA, UBN1 and ASF1a

| PRJNA192852 | ENA