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Helicobacter pylori J99

ABSTRACT: Next-Generation Sequencing Facilitates Quantitative Analysis of Wild Type and csrA Mutant Helicobacter pylori J99 Transcriptomes

PROVIDER: PRJNA375119 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR5264413.fastq.gz	Fastqsanger.gz
	SRR5264414.fastq.gz	Fastqsanger.gz
	SRR5264415.fastq.gz	Fastqsanger.gz
	SRR5264416.fastq.gz	Fastqsanger.gz
	SRR5264417.fastq.gz	Fastqsanger.gz

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Next-Generation Sequencing Facilitates Quantitative Analysis of Wild Type and csrA Mutant Helicobacter pylori J99 Transcriptomes

Project description:Purpose: The goals of this study are to clarify the CsrA-regulatory system in H. pylori by NGS-derived transcriptome profiling (RNA-seq). Method: CsrA regulatory system was determined by comparative transcriptomic analysis carried out with RNA-seq on strain J99 and csrA mutant. Results: Using an optimized data analysis workflow, fifty-three genes in the csrA mutant were found to be differentially expressed compared with the wild-type. Conclusions: Our study represents the first detailed analysis of CsrA-regulatory system in H. pylori J99.

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