Project description:<p>This study utilized neurologically normal control samples deposited in North American Brain Expression Consortium (NABEC). This top-level study, phs001300, makes available all phenotype data of the NABEC study participants. <br/>In addition, molecular data of six sub-studies are available through dbGaP: <ol> <li>NABEC Genome-Wide Genotyping - <a href="study.cgi?study_id=phs000249">phs000249</a></li> <li>NABEC Exome Sequencing - <a href="study.cgi?study_id=phs001301">phs001301</a></li> <li>NABEC CAGE Sequencing of Human Cerebral Frontal Cortex - <a href="study.cgi?study_id=phs001302">phs001302</a></li> <li>NABEC mRNA Sequencing of human Cerebral Frontal Cortex - <a href="study.cgi?study_id=phs001353">phs001353</a></li> <li>NABEC Total RNA Sequencing of human Cerebral Frontal Cortex - <a href="study.cgi?study_id=phs001354">phs001354</a></li> <li>NABEC Neurochip Genotyping - <a href="study.cgi?study_id=phs001462">phs001462</a></li> </ol> </p>
Project description:Cap analysis of gene expression (CAGE) and massive parallel sequencing were used to profile the promoterome of aged human brains from five regions, namely: caudate, frontal cortex, hippocampus, putamen and temporal cortex. 25 RNA libraries from post-mortem brain tissue (five caudate, five frontal, 5 hippocampus, 5 putamen, five temporal RNA libraries from seven individuals) were processed using CAGE protocol and CAGE tags derived from the 25 libraries were sequenced with Illumina.
Project description:Cap analysis of gene expression (CAGE) and massive parallel sequencing were used to profile the promoterome of aged human brains from five regions, namely: caudate, frontal cortex, hippocampus, putamen and temporal cortex.
Project description:Transcription profiling by high throughput sequencing of cerebellum and frontal cortex from patients of amyotrophic lateral sclerosis
