Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Ficinia spiralis

ABSTRACT: Ficinia spiralis Raw sequence reads

PROVIDER: PRJNA378666 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR5337674.fastq.gz	Fastqsanger.gz

Items per page:

1 - 1 of 1

Similar Datasets

Vallisneria spiralis

Project description:Vallisneria spiralis Raw sequence reads

| PRJNA770374 | ENA

Vallisneria spiralis

Project description:Vallisneria spiralis Raw sequence reads

| PRJNA770376 | ENA

The effects of Trichinella spiralis tropomyosin on breast cancer MCF-7 cells

Project description:The excretory-secretory proteins (ESPs) of Trichinella spiralis (T. spiralis) muscle larvae have been confirmed to exert antitumor effects by modulating host immune responses or directly acting on tumor cells. Our research group previously identified that the ESPs of T. spiralis muscle larvae contain multiple proteins potentially related to antitumor activity, among which tropomyosin (TM) has attracted our attention. This study aims to introduce TM from Trichinella spiralis (T. spiralis TM) into breast cancer MCF-7 cells via transfection technology. Furthermore, we investigated the impact of T. spiralis TM on the gene expression profile of MCF-7 cells through transcriptomics. Finally, the study systematically evaluated its regulatory effects on apoptosis, proliferation, and migration. We are the first to comprehensively evaluated the anticancer effects of T. spiralis TM on MCF-7 breast cancer cells. Our findings showed that T. spiralis TM increases apoptosis by activating the mitochondrial-mediated apoptosis pathway and inhibits cell migration and proliferation by downregulating the expression of important hub genes, including PRKACA, CDK3, VPS35, and BCAR1. These findings provide a novel theoretical basis for the application of molecules linked to Trichinella in tumor therapy and support for potential new targets.

2025-09-02 | GSE306260 | GEO

Gorgoleptis spiralis

Project description:Gorgoleptis spiralis

| PRJNA962951 | ENA

Cephalothrix spiralis

Project description:Cephalothrix spiralis

| PRJNA894686 | ENA

Differential methylation in discrete developmental stages of the parasitic nematode Trichinella spiralis

Project description:We describe the first comprehensive study confirming the existence of DNA methylation, characterising the methylomes of three life stages of the food-borne agent of human trichinellosis, Trichinella spiralis. We further identify sets of genes where the DNA methylation status varied between thedevelopmental stages that are closely related to the parasitism of the organism. Examination of DNA methylation status in three life stages (Adult, muscle larve, new born larve) of Trchinella Spiralis using MethylC-seq.

2012-09-28 | E-GEOD-39328 | biostudies-arrayexpress

Vallisneria spiralis

Project description:Vallisneria spiralis overview

| PRJNA907123 | ENA

Cephalothrix spiralis

Project description:Cephalothrix spiralis overview

| PRJNA895160 | ENA

Coemansia spiralis

Project description:Coemansia spiralis overview

| PRJNA403924 | ENA