Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Homo sapiens

ABSTRACT: ChIP-seq analysis of MCF10A cells exressing active mutant YAP-5SA

PROVIDER: PRJNA383543 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR5457800.fastq.gz	Fastqsanger.gz
	SRR5457799.fastq.gz	Fastqsanger.gz

Items per page:

1 - 2 of 2

Similar Datasets

RNA-seq on MCF10A-YAP5SA cells (overexpressed constrictively activated YAP in MCF10A cells) transduced with sgRNAs vectors targeting the TEAD4 binding motif within the identified enhancers

Project description:We performed a CRISPR-based functional genetic screen targeting TEAD4 binding motif located within the YAP-bound enhancers. The screen identified seven functional enhancers whose targeting resulted in a marked negative effect on the proliferation of MCF10A-YAP-5SA cells (overexpressed constrictively activated YAP) but no significant effect on MCF10A (parental control) cells. We then carried out RNA-seq analysis on MCF10A-YAP-5SA cells transduced with sgRNA vectors targeting these seven enhancers (enhancers A, B, C, D, E, F, G) as well as the non-targeting sgRNA as control (NT).

2021-01-01 | GSE137981 | GEO

ChIP-seq analysis of MCF10A cells exressing active mutant YAP-5SA

Project description:To understand the direct target genes YAP transcription co-activator invovled with in gonome-wide levels, next generation sequencing was conducted in Flag-YAP-5SA overexpressing MCF10A cells using Flag (sigma) antibody.

2017-07-19 | GSE97972 | GEO

E-MTAB-8247

Project description:mRNA-seq of MCF10A USP22 knockdown cells

2025-01-16 | E-MTAB-8247 | ExpressionAtlas

Homo sapiens

Project description:MCF10A YAP-OE RNA-seq analysis

| PRJNA288903 | ENA

Next Generation Sequencing of first trimester human cytotrophoblasts expressing a constitutively active mutant (5SA) of the transcriptional co-activator YAP.

Project description:Aim of the study was to elucidate YAP-regulated trophoblast-specific genes by analyzing differentially-expressed gene signatures between first trimester human cytotrophoblasts (vCTBs) transfected with a YAP-5SA mutant or a control plasmid.

2020-05-19 | GSE143858 | GEO

E-GEOD-49975

Project description:Integrative analysis of histone ChIP-seq and gene expression microarray data using Bayesian mixture models

2015-07-27 | E-GEOD-49975 | ExpressionAtlas

E-MTAB-2349

Project description:RNA-seq analysis of U2OS cells exposed to heat stress

2025-01-23 | E-MTAB-2349 | ExpressionAtlas

miRNA-seq analysis of YAP5SA overexpressed gastric epithelial cells

Project description:To investigate whether YAP upregulates MYC via miRNA repression, we sequenced miRNAs from gastric epithelial cells (HFE-145) either expressed with vector or YAP-5SA.

2018-04-23 | GSE104822 | GEO

E-MTAB-6526

Project description:RNA-Seq analysis of MCV-miR-M1 mimic-transfected HEK293 cells

2025-01-23 | E-MTAB-6526 | ExpressionAtlas

E-GEOD-51212

Project description:Whole transcriptome analysis of erlotinib treatment in EGFR-mutant cells

2025-01-24 | E-GEOD-51212 | ExpressionAtlas