Project description:Primary objectives: The primary objective is to investigate circulating tumor DNA (ctDNA) via deep sequencing for mutation detection and by whole genome sequencing for copy number analyses before start (baseline) with regorafenib and at defined time points during administration of regorafenib for treatment efficacy in colorectal cancer patients in terms of overall survival (OS).
Primary endpoints: circulating tumor DNA (ctDNA) via deep sequencing for mutation detection and by whole genome sequencing for copy number analyses before start (baseline) with regorafenib and at defined time points during administration of regorafenib for treatment efficacy in colorectal cancer patients in terms of overall survival (OS).
| 2533916 | ecrin-mdr-crc
Project description:Whole genome sequencing of three Xenorhabdus strains
| PRJNA384510 | ENA
Project description:Whole genome sequencing of Xenorhabdus griffiniae WS9
Project description:In order to study the inhibition mechanism of volatile organic compounds produced by Xenorhabdus bovienii on Fusarium solani (NK-NH1), we selected the inhibited and uninhibited Fusarium solani mycelia for transcriptome sequencing, and tried to find the corresponding inhibition mechanism at the gene level.